Organic Acids Test (The Great Plains Laboratory)

Organic acids are chemical compounds excreted in the urine of mammals that are products of metabolism. Metabolism is the sum of chemical reactions in living beings by which the body builds new molecules and breaks down molecules to eliminate waste products and produce energy. Organic acids are organic compounds that are acidic. Organic acids are substances in which carbon and hydrogen are always present but which may also contain the elements of oxygen, nitrogen, sulfur, and phosphorus as well.

The Organic Acids Test offers a comprehensive metabolic snapshot of a patient’s overall health with 75 markers.  It provides an accurate evaluation of intestinal yeast and bacteria.  Abnormally high levels of these microorganisms can cause or worsen behavior disorders, hyperactivity, movement disorders, fatigue and immune function. Many people with chronic illnesses and neurological disorders often excrete several abnormal organic acids in their urine. The cause of these high levels could include oral antibiotic use, high sugar diets, immune deficiencies, acquired infections, as well as genetic factors.

3-Oxoglutaric (female)

Optimal range: 0 - 0.33 mmol/mol creatinine

3-Oxoglutaric indicates yeast overgrowth in the gastrointestinal tract. 

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5-Hydroxymethyl-2-furoic (female)

Optimal range: 0 - 14 mmol/mol creatinine

A metabolite produced by Aspergillus and possibly other fungal species in the GI tract.

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Arabinose (female)

Optimal range: 0 - 29 mmol/mol creatinine

Breakdown product of hyaluronic acid; also found in certain foods.

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Carboxycitric (female)

Optimal range: 0 - 29 mmol/mol creatinine

Carboxycitric is a metabolite of yeast/fungi and general indicator of gastrointestinal dysbiosis. Elevated yeast/fungal metabolites indicate overgrowth in the GI tract.

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Citramalic (female)

Optimal range: 0 - 3.6 mmol/mol creatinine

Metabolite of yeast or anaerobic bacteria, including Clostridia.

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Furan-2,5-dicarboxylic (female)

Optimal range: 0 - 16 mmol/mol creatinine

Furan 2,5-dicarboxylic is a byproduct of Aspergillus and other fungal species.

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Furancarbonylglycine (female)

Optimal range: 0 - 1.9 mmol/mol creatinine

Furancarbonylglycine is a metabolite produced by Aspergillus and possibly other fungal species in the GI tract.

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Tartaric (female)

Optimal range: 0 - 4.5 mmol/mol creatinine

Breakdown product of hyaluronic acid; also found in some foods.

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Tricarballylic (female)

Optimal range: 0 - 0.44 mmol/mol creatinine

Marker for exposure to certain fungal contamination in foods.

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