Boston Heart HDL Map Test
Plasma
Performed by: Boston Heart Diagnostics
OVERVIEW OF THE HDL MAP
Standard HDL-C tests only measure the total amount of HDL-C contained by all HDL particles. Boston Heart’s exclusive HDL Map test measures the amount of apoA-I in the five most significant subpopulations, resulting in a deeper understanding of a patient’s CVD risk.
This exclusive method provides an accurate and consistent indication of reverse cholesterol transport by separating the larger, cardioprotective particles (α-1) most associated with decreased CVD risk from the smaller HDL particles which have been associated with increased risk.
The Boston Heart HDL Map® test assesses the five key HDL subpopulations linked to cardiovascular disease (CVD) risk through a unique gel electrophoresis technique. This method measures the amount of apoA-I protein in each of the five HDL subclasses, offering precise insights to identify patients at higher risk of CVD.
A low α-1 level is a critical indicator of recurrent CVD events. Studies have shown that low levels of α-1 HDL and high levels of pre ß-1 HDL are predictive of recurrent CVD events, particularly in men with low HDL-C (<40 mg/dL) and existing CVD. Notably, low α-1 HDL levels are the most significant predictor of CVD recurrence (p<0.001).
Treatment options include:
- Lifestyle modifications (if indicated)
- Low saturated fat intake (<7%)
- Low cholesterol intake (<200 mg/day)
- Low sugar intake
- Exercise for more than 30 minutes per day
- Smoking cessation
- Weight reduction (if indicated)
- Medications and their effects on HDL particles
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Biomarkers included in this panel:
a-1 (female)
Low a-1 level is a significant predictor of recurrent CVD events. The marker α-1 from the Boston Heart HDL Map test is a key player in understanding cardiovascular health. HDL, or high-density lipoprotein, often called "good cholesterol
Learn morea-2 (female)
The α-2 marker, one of the key HDL subpopulations measured by the Boston Heart HDL Map® test, plays an important role in assessing cardiovascular health. HDL, or high-density lipoprotein, is commonly known as "good cholesterol" be
Learn morea-3 (female)
The marker α-3 in the Boston Heart HDL Map Test is one of the specific subpopulations of high-density lipoprotein (HDL) particles measured to assess cardiovascular disease (CVD) risk. HDL particles, often referred to as "good cholesterol,&
Learn morea-4 (female)
Alpha-4 High-Density Lipoprotein (α-4 HDL) is a specific subtype of HDL, commonly referred to as "good cholesterol." HDL, or High-Density Lipoprotein, is a type of protein in your blood that carries fats. The "alpha-4" desig
Learn morePreb-1
What is Pre-Beta-1 HDL? Pre-Beta-1 HDL, often referred to as Pre-b-1 HDL, is a distinct form of High-Density Lipoprotein (HDL), commonly known as "good cholesterol." This specific type of HDL is unique because it is the smallest and most
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