Optimal Result: 0.42 - 2 Ratio.

A high ratio of quinolinic acid to the tryptophan metabolite, 5-hydroxyindoleacetic acid, indicates excessive inflammation due to recurrent infections, excessive tryptophan intake, immune overstimulation, excessive adrenal production of cortisol, or excessive exposure to phthalates.

What does it mean if your Quinolinic / 5-HIAA Ratio result is too low?

A low Quinolinic Acid:5-HIAA ratio is non-significant because quinolinic acid acts as a central nervous system toxin. Thus, if Quinolinic Acid and 5-HIAA are within normal limits, a low ratio is non-significant.

What does it mean if your Quinolinic / 5-HIAA Ratio result is too high?

Higher ratios indicate excessive inflammation due to:

recurrent infections

- excessive tryptophan intake

- immune overstimulation

- excessive cortisol

- or excessive phthalate exposure.

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