Cytokine Panel 13, Serum
Performed by: Quest Diagnostics
Primarily for research and to support attempts to understand the pathogenesis of immune, infectious, allergic, or inflammatory disorders.
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Biomarkers included in this panel:
IFN-γ is a helper T-cell 1 (Th1)-derived cytokine and plays a critical role for both innate and adaptive immunity against viral and intracellular bacterial infections and tumor control.
Learn moreInterleukin-1-beta, one form of interleukin-1, is made mainly by one type of white blood cell, the macrophage, and helps another type of white blood cell, the lymphocyte, fight infections. It also helps leukocytes pass through blood vessel walls to s
Learn moreInterleukin-10 is an important suppressor of immune responses. In vitro studies indicate that Interleukin-10 directly inhibits IL-2 and IL-5 production by TH1 and TH2 cells. Interleukin-10 acts as an immunosuppressor of antigen presenti
Learn moreThis family of cytokines plays crucial roles in shaping immune responses during antigen presentation and influence cell-fate decisions of differentiating naïve T cells. They also play essential roles in regulating functions of a variety of
Learn moreInterleukin 13 is a mediator of allergic inflammation and different diseases including asthma. IL-13 is implicated in numerous processes, including a) recruitment of eosinophils and M2 macrophages to the lung, b) induction of mucus secretion into
Learn moreIL-17A, commonly referred to as IL-17, is involved in normal physiological processes and is also a leading pathogenic cytokine in a wide range of pathologic conditions, including cancer and autoimmune disorders, due to its strong proinflammatory
Learn moreSoluble Interleukin 2 receptor concentration reflects the immune activation in autoimmune diseases, neoplasms (notably lymphoproliferations), and infections.
Learn moreInterleukin 2 is a pleiotropic cytokine produced primarily by mitogen- or antigen- activated T lymphocytes. Interleukin 2 plays a role in promoting the clonal expansion of antigen-specific cytotoxic and suppressor T cells. In vitro studi
Learn moreInterleukin 4 is a pleiotropic cytokine produced by activated T lymphocytes, CD3+ cells, NK-T cells, mast cells, eosinophils, and basophils. Interleukin 4 has multiple immune response modulation functions on a variety of cell types. It
Learn moreInterleukin 5 plays a critical role in the host immune response to helminthic infections and has been implicated in the pathology of certain allergic diseases, asthma, and vasculitis.
Learn moreInterleukin-6 is involved in inflammation and infection responses and also in the regulation of metabolic, regenerative, and neural processes.
Learn moreInterleukin 8 (IL-8) is a promising marker for many clinical conditions and currently being applied by various subspecialties of medicine either for the purpose of rapid diagnosis or as a predictor of prognosis. Nevertheless, IL-8 level increased as
Learn moreInterleukin-2 Receptor Alpha Chain (IL-2Ra), also known as CD25, is a protein expressed on the surface of immune cells, such as activated T-cells, B-cells, and natural killer (NK) cells. When it is shed from the surface of these cells, it circulates
Learn moreResults are used to understand the pathophysiology of immune, infectious, or inflammatory disorders, or may be used for research purposes. Tumor necrosis factor-α (cachectin) and tumor necrosis factor-β (lymphotoxin) are two closely rel
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