Organic Acids Test (The Great Plains Laboratory)

Methylmalonic (Males Age 13 and Over)

Optimal Result: 0 - 2.3 mmol/mol creatinine.

Methylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production. In one step of metabolism, vitamin B12 promotes the conversion of methylmalonyl CoA (a form of MMA) to succinyl Coenzyme A. If there is not enough B12 available, then the MMA concentration begins to rise, resulting in an increase of MMA in the blood and urine. The measurement of elevated amounts of methylmalonic acid in the blood or urine serves as a sensitive and early indicator of vitamin B12 deficiency.

References:

- https://labtestsonline.org/tests/methylmalonic-acid

What does it mean if your Methylmalonic (Males Age 13 and Over) result is too high?

If elevated, it reflects insufficient Vitamin B12.

Common symptoms if low B12:

- Fatigue,

- poor memory,

- brain fog,

- unsteady gait,

- numbness, tingling,

- and depression

Medications that interfere with or decrease B12:

- H2 Blockers and PPIs for acid

- Metformin/Glucophage

- Birth Control Pills

- Hydrocortisone and Ciprofloxacin

Treatment considerations:

- Increase B12 foods / B12 supplementation

- Consider H.Pylori/SIBO/GUT testing

- Consider serum Intrinsic Factor or Parietal Cell Antibody testing

- Consider Biotin testing (actually causes blunted MMA but B12 symptoms)

10 000+ happy clients
100% satisfaction
★ ★ ★ ★ ★ customer support

Understand blood, stool, and urine medical results from all your laboratories.

Get Started With Our Personal Plan

Advanced Plan

  • ✓ Yearly subscription
  • ✓ Five free uploads
  • ✓ Cancel anytime
  • ✓ Instant interpretations
  • ✓ Use the free self-upload form
  • ✓ 3000+ biomarkers explained
  • ✓ Nutrition Recommendations
  • ✓ Dedicated support
  • ✓ Yearly subscription
  • ✓ Five free uploads
  • ✓ Cancel anytime
$79 per year
  • ✓ Instant interpretations
  • ✓ Use the free self-upload form
  • ✓ 3000+ biomarkers explained
  • ✓ Nutrition Recommendations
  • ✓ Dedicated support

Unlimited Plan

  • ✓ No subscription
  • ✓ Ten free uploads
  • ✓ Unlimited access
  • ✓ Instant interpretations
  • ✓ Use the free self-upload form
  • ✓ 3000+ biomarkers explained
  • ✓ Nutrition Recommendations
  • ✓ Dedicated support
  • ✓ No subscription
  • ✓ Ten free uploads
  • ✓ Unlimited access
$250 full version

Are You a Health Professional?

Get started with our professional plan

Welcome to Healthmatters Pro.

Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place. Learn more

Pro Plan

for health professionals

  • ✓ Track multiple clients results
  • ✓ No setup fees
  • ✓ No hidden costs
  • ✓ Cancel anytime
  • ✓ Instant interpretations
  • ✓ Use the free template forms
  • ✓ 3000+ biomarkers explained
  • ✓ Additional team member $25
  • ✓ Personal training and support

$45 per month

Use promo code to save 10% off any plan.


We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

×

Understand Your Lab Result Now

  • Instant interpretation
  • 3000+ biomarkers explained
  • Science-based recommendations
  • Online support
  • Secure and private portal

Get 10% off with promocode: