Mycotoxins (Vibrant America)

The Vibrant Mycotoxins test is a urine-based assay for 31 of the most common mycotoxins produced by molds to which humans are exposed.

Individuals most at risk for mycotoxin exposure include those who live or work in older buildings, those who have known exposure to water-damaged buildings, and those with impaired immune responses or higher levels of oxidative stress.

Mycotoxins complicate human health in a number of ways and their presence in the human body can lead to a number of serious health concerns, including autoimmune disease and cancer.

There may be higher incidence of autoimmune or neurological symptoms in your patients with mycotoxin toxicity. Consider screening for Hashimoto’s thyroiditis, connective tissue disorders, celiac disease, and neurological autoimmunity along with mycotoxin testing.

Treatment of mycotoxin exposure should include a holistic approach to eradicate the mold from the individual, thorough and professional removal of mold from environmental sources, and continued testing to monitor reductions in mycotoxin levels post-intervention.

Due to the common co-occurrence of Lyme and mycotoxin exposure from depressed immunity in affected individuals, as well as symptom overlap between tickborne diseases and mycotoxins, consider running the Vibrant Tickborne Diseases panel along with the Vibrant Mycotoxins test.

Aflatoxin G1

Optimal range: 0 - 4.9 ng/g

Aflatoxins are naturally occurring Mycotoxins that are produced by Aspergillus species of fungi. Aflatoxin G1 (AFG1) is one of the four major naturally known aflatoxins produced by the Aspergillus species.

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Aflatoxin M1

Optimal range: 0 - 4.8 ng/g

Aflatoxin M1 (AFM1) is the main metabolite of aflatoxin B1, which is a mycotoxin produced by the mold species Aspergillus. Aflatoxins are some of the most carcinogenic substances in the environment. Aflatoxin susceptibility is dependent on multiple different factors such as age, sex, and diet.

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Deoxynivalenol (Vomitoxin/DON)

Optimal range: 0 - 50.6 Units

Deoxynivalenol (DON), also known as Deoxynivalenol, a tricothecene mycotoxin, is produced by several species of Fusarium. DON has been associated with outbreaks of acute gastrointestinal illness in humans. The FDA advisory level for DON for human consumption is 1 ppm.

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diacetoxyscirpenol (DAS)

Optimal range: 0 - 3.2 ng/g

Diacetoxyscirpenol (DAS), also known as anguidine, is a type A trichothecene mycotoxin primarily produced by Fusarium fungi. Trichothecenes are known as major contaminants of cereals and cereal-containing foods.

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Fumonisins B1

Optimal range: 0 - 4.6 ng/g

Fumonisins B2

Optimal range: 0 - 5.4 ng/g

Fumonisin B2 is a mycotoxin produced by Fusarium growing on moldy corn (maize) grain. FB2 and Fumonisin B3 (FB3) occur in lower concentrations than FB1. FB1 and FB2 are approximately equal in structure and toxicity but naturally occur in a ratio of about 3: 1 for FB1/FB2, thus has less toxicity than FB1.

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Fumonisins B3

Optimal range: 0 - 8.1 ng/g

Gliotoxin

Optimal range: 0 - 155.9 ng/g

Gliotoxin is produced by the mold genus Aspergillus. Aspergillus spreads in the environment by releasing conidia which are capable of infiltrating the small alveolar airways of individuals.

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Nivalenol (NIV)

Optimal range: 0 - 2.4 Units

Produced by the mold genus Fusarium, the type B trichothecenes, nivalenol (NIV) and their acetylated precursors are often contaminating cereal staples, posing a potential threat to public health that is still incompletely understood.

Trichothecenes are very resistant to milling and processing, they can enter human food products easily. NIV is not found in food as commonly as DON; however, it demonstrates higher toxicity in animal studies. The toxicity of NIV is often compared to the toxicity of DON; however, the amount of toxicological data on NIV impact is much lower compared to DON.

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Patulin

Optimal range: 0 - 8.7 ng/g

Patulin is a mycotoxin associated with the spoilage of grains, fruits, cheeses, and breads. It is considered the most significant mycotoxin in fruit and fruit juices; important because high-risk populations such as infants, children and the elderly consume these products. 

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