Arabinose (Males Under Age 13)
Arabinose is a breakdown product of hyaluronic acid; also found in certain foods. Arabinose is a five-carbon sugar with the function of the aldehyde called aldose. It is suspected that the arabitol produced by yeasts in the gastrointestinal tract is absorbed in the portal circulation, and is then converted into arabinose by the liver. It is not metabolized endogenously and is eliminated by the urine, so consequently high levels of arabinose in the urine may be a good indicator of Candida infections.
What does it mean if your Arabinose (Males Under Age 13) result is too high?
Elevated arabinose levels on an Organic Acids Test (such as the one by Mosaic Diagnostics) in a male under age 13 typically indicate a fungal or yeast overgrowth in the gastrointestinal tract. Arabinose is a sugar metabolite produced mainly by Candida species and other yeast organisms. When these organisms grow excessively, arabinose levels in urine often rise.
Clinical implications of elevated arabinose in children:
-
Candida or fungal overgrowth:
The most common cause is gastrointestinal yeast overgrowth, frequently Candida albicans. Children might exhibit digestive symptoms (bloating, gas, constipation, diarrhea), behavioral or cognitive changes (hyperactivity, irritability, attention difficulties), skin rashes, recurrent infections, or fatigue. -
Potential gut dysbiosis:
Elevated arabinose may indicate disrupted gut flora balance, possibly due to antibiotic use, high sugar diets, or compromised immunity. -
Influence on neurological and behavioral health:
Candida overgrowth and elevated arabinose levels have been associated with symptoms similar to those seen in children diagnosed with autism spectrum disorders, ADHD, or other developmental conditions.
Recommended next steps:
- Dietary adjustments: Reduce sugar and refined carbohydrates to limit yeast proliferation.
- Probiotics and gut-supportive nutrients: Introduce beneficial bacteria through probiotics or fermented foods.
- Antifungal treatment: Consider natural antifungals (such as caprylic acid, oregano oil, or grapefruit seed extract) or pharmaceutical antifungals under the guidance of a healthcare provider.
- Further clinical evaluation: Consult a practitioner knowledgeable in pediatric gut health to determine underlying causes and appropriate interventions.
Elevated arabinose is a valuable marker indicating a need for improved gut microbiome balance, particularly in young children.
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