A healthy result should fall into the range 0.04 - 0.36 mmol/mol creatinine.
Elevation indicates riboflavin deficiency (vitamin B2), a common factor in moderate urinary increases of glutaric acid.
Other possible factors include:
- fatty acid oxidation defects
- metabolic effects of valproic acid (Depakene),
- or celiac disease.
The probability of a genetic disease is higher with very high values.
The use of dietary supplements containing riboflavin and coenzyme Q10 may improve clinical symptoms.
This compound may be elevated in about 10% of children with autism.
insert the value from you Glutaric test result.
Elevation indicates riboflavin (vitamin B2) deficiency. Other possible factors include fatty acid oxidation defects, and metabolic effects of valproic acid (Depakene), or celiac disease. The probability of a genetic disease is higher with very high values. The use of dietary supplements containing riboflavin and coenzyme Q10 may improve clinical symptoms. This compound may be elevated in about 10% of children with autism.
Possible causes:
- Low B2
- Inborn error of metabolism
- Associated with CETP genetic polymorphism
Additional investigations:
- Red blood cell B2
- Genetic Diagnostic Testing
Treatment considerations:
- Supplement B2
- Consider mitochondrial support nutrients (e.g. CoQ10
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2-Hydroxybutyric, 2-Hydroxyhippuric, 2-Hydroxyisocaproic, 2-Hydroxyisovaleric, 2-Hydroxyphenylacetic, 2-Oxo-4-methiolbutyric, 2-Oxoglutaric, 2-Oxoisocaproic, 2-Oxoisovaleric, 3-Hydroxy-3-methylglutaric (HMG), 3-Hydroxybutyric, 3-Hydroxyglutaric, 3-Indoleacetic, 3-Methyl-2-oxovaleric, 3-Methylglutaconic, 3-Methylglutaric, 3-Oxoglutaric, 4-Cresol, 4-Hydroxybenzoic, 4-Hydroxybutyric, 4-Hydroxyhippuric, 4-Hydroxyphenylacetic, 4-Hydroxyphenyllactic, 5-Hydroxyindoleacetic (5-HIAA), 5-Hydroxymethyl-2-furoic, Acetoacetic, Aconitic, Adipic, Arabinose, Ascorbic, Carboxycitric, Citramalic, Citric, DHPPA (Beneficial Bacteria), Ethylmalonic, Fumaric, Furan-2,5-dicarboxylic, Furancarbonylglycine, Glutaric, Glyceric, Glycolic, Hippuric, Homogentisic, Homovanillic (HVA), HPHPA, HVA / VMA Ratio, Kynurenic, Lactic, Malic, Malonic, Mandelic, Methylcitric, Methylmalonic, Methylsuccinic, N-Acetylaspartic, N-Acetylcysteine (NAC), Orotic, Oxalic, Pantothenic (B5), Phenyllactic, Phenylpyruvic, Phosphoric, Pyridoxic (B6), Pyroglutamic, Pyruvic, Quinolinic, Quinolinic / 5-HIAA Ratio, Sebacic, Suberic, Succinic, Tartaric, Thymine, Tricarballylic, Uracil, Vanillylmandelic (VMA)
