Adrenal Function Profile; saliva (Labrix, Doctor's Data)

This profile provides a comprehensive view of HPA axis/adrenal function and includes 4 cortisol levels collected over the course of the day, plus DHEA.

Cortisol levels should be at their highest level 30 minutes after waking up in the morning, decreasing gradually over the course of the day, reaching their lowest point at bedtime. The resulting curve or pattern allows health care providers to pinpoint issues with adrenal gland function. Alterations in this pattern can result in symptoms related to stress, fatigue and insomnia.

DHEA levels naturally decline with age, although alterations can be seen as part of the stres response.

Cortisol AM30

Optimal range: 14 - 25 nmol/L

Cortisol is a stress hormone produced by the adrenal glands and is the primary agent used in our body’s flight or fight response to threatening stimuli.

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Cortisol Evening

Optimal range: 2 - 5 nmol/L

This is the 3rd cortisol sample of the day. Usually measured in the evening. 

Cortisol is a hormone produced by the adrenal glands, which are located on top of the kidneys. It is normally released in response to events and circumstances such as waking up in the morning, exercising, and acute stress.

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Cortisol Night

Optimal range: 1 - 4 nmol/L

This is the 4th cortisol sample of the day (=night).

Cortisol is a hormone produced by the adrenal glands, which are located on top of the kidneys. It is normally released in response to events and circumstances such as waking up in the morning, exercising, and acute stress.

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Cortisol Noon

Optimal range: 5 - 10 nmol/L

Cortisol is a stress hormone produced by the adrenal glands and is the primary agent used in our body’s flight or fight response to threatening stimuli.

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DHEA

Optimal range: 106 - 300 pg/mL

DHEA levels peak at around age 25, then decline steadily through the following decades. DHEA can be converted downstream in the steroidogenic pathway to create androgens and estrogens. It has antioxidant and anti-inflammatory properties and can be protective against corticosterone’s neurotoxic effects.

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