3000 NutrEval FMV - Urine and Blood
Performed by: Genova Diagnostics
NutrEval® Profile Test: Comprehensive Nutritional & Functional Assessment
The NutrEval® Profile is an advanced nutritional and functional medicine test designed to uncover the root causes of metabolic dysfunction, nutrient deficiencies, and biochemical imbalances. By evaluating how nutrients are absorbed, metabolized, and utilized at the cellular level, NutrEval provides clinicians and patients with actionable insights to support personalized nutrition, targeted supplementation, and long-term health optimization.
Recognized as one of the most comprehensive nutritional assessments available, the NutrEval Profile goes far beyond standard blood tests by integrating functional biomarkers from both blood and urine samples.
What Is the NutrEval® Profile?
The NutrEval Profile is a systems-based nutritional assessment that analyzes over 125 biomarkers related to energy production, digestion, detoxification, oxidative stress, and nutrient status. Rather than looking at isolated lab values, NutrEval evaluates biochemical pathways, helping clinicians identify patterns that may contribute to chronic symptoms or suboptimal health.
What Does the NutrEval Test Measure?
NutrEval assesses multiple categories of biomarkers to create a comprehensive picture of nutritional and metabolic health.
Organic Acids
Organic acid markers reflect mitochondrial energy production, gut microbial activity, detoxification capacity, and oxidative stress. These markers can reveal inefficient metabolism, microbial imbalances, and nutrient cofactor needs.
Amino Acids
Amino acid analysis evaluates essential and non-essential amino acids, providing insight into protein digestion, neurotransmitter synthesis, immune function, muscle repair, and metabolic balance.
Fatty Acids
Fatty acid testing examines essential fatty acid intake and metabolism, including omega-3 and omega-6 balance. These markers are closely linked to inflammation, cardiovascular health, and cell membrane integrity.
Oxidative Stress Markers
Oxidative stress biomarkers assess the balance between free radical production and antioxidant defenses, which plays a role in aging, chronic disease risk, and cellular damage.
Nutrient & Toxic Elements
NutrEval measures essential minerals such as magnesium, zinc, and selenium, while also evaluating exposure to toxic elements like mercury, lead, and arsenic, helping identify both deficiencies and toxic burden.
How Does NutrEval Testing Work?
NutrEval combines intracellular, extracellular, functional, and direct nutrient measurements into a single, integrated report. Its proprietary algorithm synthesizes results across multiple pathways and generates personalized nutrient recommendations based on individual biochemical needs.
Unlike standard nutrient panels, NutrEval focuses on how nutrients function, not just whether they fall within reference ranges.
Why Choose the NutrEval Profile?
Key Benefits of NutrEval Testing
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Comprehensive Nutrient Analysis
Evaluates over 40 critical nutrients, including vitamins, minerals, amino acids, antioxidants, and essential fatty acids. -
Personalized Nutritional Recommendations
Data-driven dietary and supplementation guidance tailored to individual metabolic patterns. -
Functional Imbalance Scores
Highlights mitochondrial dysfunction, oxidative stress, impaired detoxification, and nutrient insufficiencies. -
Biochemical Pathway Visuals
Clear charts that help patients and clinicians understand complex metabolic interactions. -
Educational Clinical Insights
Detailed explanations of nutrient functions, deficiency drivers, and dietary sources.
Who Should Consider NutrEval Testing?
The NutrEval Profile is especially helpful for individuals with complex, chronic, or unexplained health concerns, including:
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Fatigue and Low Energy – Often linked to mitochondrial dysfunction or micronutrient gaps
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Mood Disorders and Cognitive Concerns – Nutrient imbalances affecting neurotransmitter production
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Cardiovascular Risk – Fatty acid imbalances and oxidative stress markers
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Diabetes and Insulin Resistance – Metabolic inefficiencies affecting glucose regulation
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Digestive Issues and Maldigestion – Poor nutrient absorption or gut-related dysfunction
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Athletic Performance and Recovery – Optimizing nutrient status for performance and repair
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Malnutrition or Restrictive Diets – Identifying deficiencies despite adequate caloric intake
NutrEval Subpanels
For more targeted assessments, NutrEval also offers focused subpanels, including:
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Organic Acids
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Amino Acids
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Fatty Acids
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Oxidative Stress Markers
These subpanels allow clinicians to investigate specific areas of concern without ordering a full NutrEval Profile.
What Samples Are Required?
The NutrEval test typically requires a combination of blood and urine samples. Collection instructions may vary depending on the version of the test and should be followed carefully to ensure accurate results.
How to Use NutrEval Results
NutrEval results are used by healthcare providers to:
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Identify nutrient deficiencies and excesses
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Detect metabolic and mitochondrial inefficiencies
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Assess oxidative stress and detoxification capacity
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Develop personalized nutrition and supplementation plans
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Monitor progress over time
NutrEval is intended to be interpreted alongside symptoms, medical history, and other laboratory data.
NutrEval Test FAQs
What is the NutrEval® Profile test?
The NutrEval Profile is a comprehensive nutritional and functional assessment that evaluates biomarkers related to nutrient status, metabolism, oxidative stress, and detoxification using blood and urine samples.
How is NutrEval different from standard nutrient testing?
Standard nutrient tests typically measure isolated vitamin or mineral levels. NutrEval integrates functional biomarkers that reflect biochemical pathway performance, helping identify root-cause patterns rather than single abnormalities.
How many biomarkers does NutrEval include?
NutrEval assesses 125+ biomarkers, though the exact number may vary depending on the test version and subpanels ordered.
Does NutrEval test for heavy metals?
NutrEval includes nutrient and toxic element assessment, which may evaluate exposure to certain heavy metals. Marker availability can vary by test version.
Who should not use NutrEval as a diagnostic tool?
NutrEval is not designed to diagnose disease on its own. It is a functional assessment tool that should be interpreted by a qualified clinician in the context of symptoms and other diagnostic findings.
How long does it take to receive results?
Turnaround time varies by laboratory and logistics. Your healthcare provider can provide the most accurate estimate.
Personalized Nutritional Support for Long-Term Health
The NutrEval Profile is designed to do more than identify abnormalities—it helps restore optimal biological function. By addressing underlying nutritional and biochemical imbalances, NutrEval supports improvements in energy production, digestion, detoxification, cognitive function, immune resilience, and overall vitality.
If you’re seeking a deeply personalized nutritional assessment, the NutrEval Profile is a powerful tool for supporting long-term health and preventing chronic disease.
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Biomarkers included in this panel:
1-methylhistidine is derived from the dipeptide anserine (which consists of the amino acids 1-methylhistidine and beta-alanine). Anserine and its derivatives are associated with the consumption of poultry and fish. Both 1-methylhistidine and 3-methyl
Learn moreBoth 1-methylhistidine and 3-methylhistidine are histidine metabolites which have been proposed as markers of meat intake. Note that some confusion exists in the literature regarding the numbering of atoms in the imidazole ring of histidine &ndash
Learn moreAlpha-Amino-N-butyric acid (α-ANB), also known as alphaaminobutyric acid, is a nonessential amino acid derived from the catabolism of methionine, threonine, and serine. α-ANB is both formed and metabolized by reactions which require vi
Learn moreAlpha-aminoadipic acid (also known as 2-aminoadipic acid) is an intermediary biomarker of lysine and tryptophan metabolism. The further metabolism of alpha-aminoadipic acid to alpha-ketoadipic acid requires vitamin B6. Plasma alpha-aminoadipic aci
Learn moreAlanine is a nonessential amino acid. It is the second most abundant amino acid in circulation, after glutamine. It is found in many foods including eggs, meat, lentils, and fish. Alanine is involved in sugar metabolism for energy and is import
Learn moreArginine is found in all protein foods and is very abundant in seeds and nuts. It is considered a semi-essential amino acid during early development, infection/inflammation, or renal and/or intestinal impairment. It has many functions in the body inc
Learn moreAsparagine is a non-essential protein amino acid that is present in many fruits and vegetables including asparagus, from which it gets its name. Other dietary sources include meat, potatoes, eggs, nuts, and dairy. It can also be formed from aspart
Learn moreAspartic acid is a nonessential amino acid that plays roles in many important metabolic processes, such as energy production (citric acid cycle), hormone metabolism, CNS activation, and the urea cycle. It is found in many protein sources such as oyst
Learn moreβ-alanine is a breakdown product of carnosine and anserine, which are dipeptides from meat consumption. Although β-alanine’s properties are limited, its relationship to carnosine makes it important. Both have antioxidant properties. A
Learn moreBeta-aminoisobutyric acid (also known as 3-aminoisobutyric acid) is a non-protein amino acid formed by the catabolism of valine and the nucleotide thymine. It is further catabolized to methylmalonic acid semialdehyde and propionyl-CoA. Levels are
Learn moreCitrulline is an intermediate, nonprotein-forming amino acid in the urea cycle serving as a precursor to arginine. It derives its name from the watermelon (Citrullus vulgaris), where it was first isolated and identified. It is easily absorbed by t
Learn moreCysteine is a nonessential sulfur-containing amino acid. It is obtained from the diet and is also endogenously made from the intermediate amino acid cystathionine. Dietary cysteine sources include poultry, eggs, beef, and whole grains. This ami
Learn moreCystathionine is an intermediate dipeptide within the process of transsulfuration. Transsulfuration is the main route for irreversible homocysteine disposal, glutathione production, and energy. The initial step involves the enzyme cystathionine &b
Learn moreEthanolamine is an intermediary metabolite in the serine-to-choline sequence. It can be used to synthesize phosphatidylethanolamine (PE), a very important membrane phospholipid. Ethanolamine is not only a precursor, but also a breakdown product of PE
Learn moreGamma-aminobutyric acid (GABA) is an amino acid that functions as an inhibitory neurotransmitter. It serves one-third of brain neurons and is involved in depression and mania. Although there are some dietary supplement and food sources for GABA (c
Learn moreGlutamic acid is a nonessential amino acid is derived from the diet and from the breakdown of gut proteins. Glutamate is a major excitatory neurotransmitter in the brain. It plays a role in neuronal differentiation, migration, and survival in the
Learn moreGlutamine is a nonessential amino acid and is the most abundant amino acid in the body. It is formed from glutamate using the enzyme glutamine synthetase. Approximately 80% of glutamine is found in the skeletal muscle, and this concentration is 30
Learn moreGlycine is a nonessential amino acid that is synthesized from choline, serine, hydroxyproline, and threonine. It has many important physiologic functions. It is one of three amino acids that make up glutathione. Glycine’s dietary sources inc
Learn moreHistidine is a semi-essential amino acid which is formed in the breakdown of carnosine. Red meat is a common source of carnosine, and therefore histadine. Other food sources include poultry, fish, nuts, seeds, and grains. Histidine and hista
Learn moreBranched Chain Amino Acids (Isoleucine, Leucine, Valine) are the three branched chain amino acids (BCAAs). Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat, grains, and dairy). No
Learn moreBranched Chain Amino Acids (Isoleucine, Leucine, Valine) Isoleucine, leucine and valine are the three branched chain amino acids (BCAAs). Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat,
Learn moreLysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes. Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed f
Learn moreMethionine is an essential amino acid that plays an important role in the methylation cycle. Methionine is obtained from dietary intake or through homocysteine remethylation. Methionine’s dietary sources include eggs, fish, meats, Brazil nuts,
Learn moreOrnithine is an intermediate nonprotein-forming amino acid of the urea cycle. Arginine is converted to ornithine via the arginase enzyme, with urea as a byproduct. Ornithine combined with carbamoyl phosphate is then converted into citrulline via t
Learn morePhenylalanine is an essential amino acid found in most foods which contain protein such as meat, fish, lentils, vegetables, and dairy. Phenylalanine is the precursor to another amino acid, tyrosine. Because tyrosine is needed to form several
Learn morePhosphoethanolamine is an intermediate in the serineto-choline sequence. It is both a precursor and byproduct of phospholipid biosynthesis and breakdown. As a precursor to the phospholipid phosphatidylethanolamine, phosphoethanolamine plays a key rol
Learn morePhosphoserine is the phosphorylated ester of the amino acid serine. The addition of a phosphoryl group to an amino acid, or its removal, plays a role in cell signaling and metabolism. Phosphoserine is a byproduct of glycolysis and subsequent intermed
Learn moreProline is a nonessential amino acid. It contains a secondary α-imino group and is sometimes called an α-imino acid. Proline, and its metabolite hydroxyproline, constitute a third of the total amino acids found in collagen. Lysine, pro
Learn moreSarcosine is an amino acid made within the methylation cycle when S-adenosylmethionine (SAM) is conjugated with glycine. It can also be made by catabolism of dimethylglycine (DMG). There are many dietary sources of sarcosine including eggs, legume
Learn moreSerine is found in soybeans, nuts, eggs, lentils, shellfish, and meats. Serine is a nonessential amino acid used in protein biosynthesis and can be derived from four possible sources: dietary intake, degradation of protein and phospholipids, biosy
Learn moreTaurine differs from other amino acids because a sulfur group replaces the carboxyl group of what would be the nonessential amino acid, β-alanine. It takes part in biochemical reactions and is not fully incorporated into proteins. In most tis
Learn moreThreonine is a large neutral amino acid and a precursor for the amino acid glycine. Foods that contain relatively high amounts of threonine include cheeses (especially Swiss), meat, fish, poultry, seeds, walnuts, cashews, almonds and peanuts. Thre
Learn moreTryptophan is involved in serotonin production via vitamin B6-dependent pathways resulting in the intermediate 5-hydroxytryptophan (5-HTP). 5-HTP is often used as a supplement for serotonin formation instead of tryptophan, which can be quickly metabo
Learn moreTyrosine is a conditionally essential amino acid which can come directly from the digestion of dietary protein. Common food sources include dairy, beans, whole grains, meat, and nuts. If intake is insufficient, tyrosine can be formed from the e
Learn moreUrea is a nontoxic byproduct of nitrogen (ammonia) detoxification. It is formed in the liver via the urea cycle and is the end product of protein metabolism. It is essentially a waste product with no physiological function.
Learn moreBranched Chain Amino Acids (Isoleucine, Leucine, Valine) Isoleucine, leucine and valine are the three branched chain amino acids (BCAAs). Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat,
Learn more