Quest Diagnostics

Performed by: Quest Diagnostics

Biomarkers included in this panel:

21-Hydroxylase Antibodies

This result is a qualitative determination of autoantibodies to 21-Hydroxylase (21-OH Abs) in patient serum. 21-OH Abs occur in autoimmune Addison's disease, whether isolated or part of type I or type II autoimmune polyglandular syndrome. This re

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Acetylcholine Receptor Ganglionic (Alpha 3) AB

Acetylcholine receptor (AChR) antibodies are autoantibodies produced by the immune system that mistakenly target proteins called acetylcholine receptors that are located on muscles that you can consciously or voluntarily control (known as skeletal mu

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Adamts13 Activity

The ADAMTS13 activity and inhibitor assays are useful for the diagnosis of congenital or acquired form of TTP. ADAMTS13 is a plasma protein responsible for regulating the interaction of platelets with von Willebrand factor (VWF) and physiologic pr

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Alpha 2 Antiplasmin

This test is used for the chromogenic determination of plasmin inhibitor (alpha 2-antiplasmin) activity in human plasma. Alpha 2-antiplasmin is the major fast-acting inhibitor of the fibrinolytic enzyme plasmin and an important regulator of the fibri

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Ana Pattern

Usually, the results of the ANA test are reported in titers and patterns. The titer gives information about how many times the lab technician diluted the blood plasma to get a sample of ANAs. The pattern of the ANA test can give information about

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AnaChoice Screen

Blood

The ANAchoice Screen is a diagnostic test The ANAchoice Screen is a diagnostic test used to detect the presence of antinuclear antibodies (ANA) in the blood. ANAs are a group of antibodies that bind to certain contents of the nucleus of the cell and

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Arachidonic Acid

Arachidonic acid (AA) is a key omega-6 fatty acid measured in the OmegaCheck test offered by Cleveland HeartLab, which assesses cardiovascular risk based on polyunsaturated fatty acid (PUFA) status.

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B2 GLYCOPROTEIN I (IGA)AB

Beta-2 glycoprotein 1 antibody is an autoantibody that is associated with inappropriate blood clotting. This test detects and measures one class (IgA) of beta-2 glycoprotein 1 antibodies.

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B2 GLYCOPROTEIN I (IGG)AB

The antiphospholipid antibody syndrome (APS) is a clinical-pathologic correlation that includes a clinical event (e.g. thrombosis, pregnancy loss, thrombocytopenia) and persistent positive antiphospholipid antibodies (IgM or IgG ACA >40 MPL/GPL,Ig

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B2 GLYCOPROTEIN I (IGM)AB

The assay contributes to the diagnosis of antiphospholipid syndrome (APS). The clinical symptoms of APS alone are not sufficiently specific to make a definitive diagnosis. Laboratory tests thus play an important role in the diagnosis of the disease.

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Beta 2 Transferrin

The diagnosis of cerebrospinal fluid (CSF) rhinorrhea or otorrhea (leakage of CSF into the nose or ear canal, usually as a result of head trauma, tumor, congenital malformation, or surgery) is often difficult to confirm. Traditional ch

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CARNITINE ESTERS

Chromogranin A (CgA)

Serum

Chromogranin-A (CgA) is an acidic glycoprotein expressed in the secretory granules of most normal and neoplastic neuroendocrine (NE) cell types, where it is released together with peptide hormones and biogenic amines. Neuroendocrine tumors (NETs) are

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COPEPTIN

Cortisol, Free, Urine

Cortisol is a steroid hormone synthesized from cholesterol by a multienzyme cascade in the adrenal glands. It is the main glucocorticoid in humans and acts as a gene transcription factor influencing a multitude of cellular responses in virtually all

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CORTISOL,FREE,LC/MS,S

Cortisol, the main glucocorticoid (representing 75%-95% of the plasma corticoids), plays a critical role in glucose metabolism and in the body's response to stress. The majority of cortisol circulates bound to corticosteroid-binding globulin (

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DNA Ab (ds) Crithidia, IFA

Confirmation testing for dsDNA IgG antibodies in patients with clinical features of systemic lupus erythematosus or at-risk for disease.

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EPA/ARACHIDONIC ACID Ratio

The EPA (Eicosapentaenoic Acid) to Arachidonic Acid ratio is a measure often used to gauge the balance of anti-inflammatory and pro-inflammatory fatty acids in the body. Eicosapentaenoic Acid (EPA) is an omega-3 fatty acid primarily found in fatty

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ESTERIFIED/FREE RATIO

Carnitine, an amino acid synthesized in animal tissues from lysine and methionine by an iron-ascorbate dependent pathway, functions as a carrier of fatty acids across cell membranes. Serum carnitine analysis is useful in the diagnosis and monitori

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ESTRADIOL (Quest)

GLUCOSE-6-PHOSPHATE DEHYDROGENASE

GLUCOSE-6-PHOSPHATE DEHYDROGENASE helps red blood cells (RBCs) function normally. It also protects them from potentially harmful byproducts that can accumulate when your body is fighting infection or as the result of certain medications. A lack of GL

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Glutamic Acid Decarboxylase 65 AB

This test is intended for the semiquantitative determination of glutamic acid decarboxylase (GAD) antibody in human serum; it is useful as an aid in the diagnosis of type 1 diabetes mellitus (autoimmune mediated diabetes).

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Helicobacter Pylori, Urea Breath Test

The urea breath test can be used to aid in the diagnosis of H pylori infection. The test can also be used to assess therapy when it is administered more than a month after completion of therapy.

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Hexagonal Phase Confirm

The Hexagonal Phase Confirm test is a specific laboratory test used to detect lupus anticoagulant (LA), which is a type of antibody associated with antiphospholipid syndrome and other autoimmune disorders. The term "Hexagonal Phase" refers

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HISTAMINE RELEASE (CHRONIC URTICARIA)

Chronic Urticaria (CU) is a common skin disorder affecting 1 to 6% of the general population.

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HISTAMINE, PLASMA

Useful for evaluating for diseases of immediate hypersensitivity or mast cell proliferation (mastocytosis).

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IGF 1, LC/MS

IMMUNOGLOBULIN M

Immunoglobulin M (IgM), which is found mainly in the blood and lymph fluid, is the first antibody to be made by the body to fight a new infection. Expressed on the surface of B cells (monomer) and in a secreted form (pentamer) with very high avi

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Immunoglobulin Subclass 4

IgG immunoglobulins are composed of four subtypes named IgG1, IgG2, IgG3 and IgG4. Each subclass is present in the serum in different concentrations, varies with age, and has different roles for immune response. Abnormal levels of one or more subclas

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LH

Lithium

This test measures the amount of lithium in the blood. Lithium is used to treat manic-depressive disorders and the manic phase of affective disorders, including mania. The therapeutic window is relatively small. Therapeutic drug monitoring is usef

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LKM-1 Antibody (IgG)

Liver Kidney Microsomal (LKM-1) Antibody (IgG) The presence of LKM-1 antibodies can be used in conjunction with clinical findings and other laboratory tests to aid in the diagnosis of autoimmune liver diseases such as autoimmune hepa

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LUPUS ANTICOAGULANT

Metanephrine, Free

To help diagnose or rule out a rare tumor of the adrenal gland called a pheochromocytoma or a rare tumor occurring outside the adrenal glands called a paraganglioma; these tumors (PPGL) produce excess hormones called catecholamines, which are broken

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Mutated Citrullinated Vimentin (MCV) Ab

Mutated citrullinated vimentin (MCV) antibody is a specific type of autoantibody that has gained attention in the context of rheumatology, particularly in the diagnosis and management of rheumatoid arthritis (RA). Citrullination is a post-translation

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Neuron Specific Enolase (NSE)

Neuron-specific enolase (NSE) is an enzyme that is found in the cytoplasm of neurons and neuroendocrine cells. The production of NSE occurs late in neural differentiation, thus making NSE an index of neural maturation.

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Normetanephrine, Free

Normetanephrine is an important metabolite of norepinephrine and serves as a marker for the activity of the sympathetic nervous system. Measuring normetanephrine levels can provide valuable information for diagnosing and managing certain medical cond

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NT PROBNP

NT-proBNP is a diagnostic screening tool to differentiate between people with normal and reduced left ventricular systolic function. - N-terminal (NT)-pro hormone BNP (NT-proBNP) is a non-active prohormone that is released from the same molec

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OMEGA 3 (EPA+DHA) INDEX

Risk: Optimal > 3.2%; Moderate 2.2-3.2%; High < 2.2% The Omega-3 Index test by Quest Diagnostics measures the levels of omega-3 fatty acids in the serum, with a focus on eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are e

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OMEGA 6/OMEGA 3 Ratio

Omega-6:Omega-3 ratio is calculated by dividing the sum of all the omega-6 fatty acids by the sum of all the omega-3 fatty acids. Omega 6 and 3 are two essential fats that are categorized as polyunsaturated fatty acids, or PUFAs for shor

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Parathyroid Hormone, intact

Interpretive Guide Intact PTH Calcium Normal Parathyroid Normal Normal Hypoparathyroidism Low or Low Normal

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PARTIAL THROMBOPLASTIN TIME, ACTIVATED

PREGNENOLONE, LC/MS

Pregnenolone is a chemical substance that is a precursor to all steroid hormones.

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PROGESTERONE, LC/MS

PROSTAGLANDIN D2 (PG D2), URINE

Prostaglandin E2, Serum/Plasma

Prostaglandins are lipid autacoids derived from arachidonic acid. They both sustain homeostatic functions and mediate pathogenic mechanisms, including the inflammatory response. 

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PROSTAGLANDINS (PG D2), SERUM/PLASMA

PROSTAGLANDINS: (PLASMA/SERUM)

PROTHROMBIN ANTIBODY (IGG)

Ribosomal P Antibody

Anti-ribosomal P proteins antibody (anti-rib P) is a highly specific marker for systemic lupus erythematosus (SLE) and it is associated with liver involvement in this disease.

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Soluble Liver Antigen (SLA) Autoantibody

Anti-soluble liver antigen antibodies are detected in 10% - 30% of patients with type 1 autoimmune hepatitis (AIH), but not in patients with type 2 AIH, primary sclerosing cholangitis or primary biliary cirrhosis.

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T3 REVERSE, LC/MS/MS

T3, FREE

Total Glutathione

Glutathione is an antioxidant, a type of chemical which helps to boost your immune system as well as prevent and reverse cellular damage.  Unlike most antioxidants which come from the food you eat, glutathione is naturally produced by the body i

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Total, Free (MN+NMN)

The marker "Total, Free (MN+NMN)" typically refers to the measurement of both metanephrine (MN) and normetanephrine (NMN) levels in a biological sample, such as blood or urine. These two compounds, metanephrine and normetanephrine, are meta

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TRYPTASE

Tryptase is an enzyme that is released, along with histamine and other chemicals, from mast cells when they are activated as part of a normal immune response as well as in allergic (hypersensitivity) responses.

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TSI - Thyroid-Stimulating Immunoglobulin, Serum

TSI stands for thyroid stimulating immunoglobulin. TSIs are antibodies that tell the thyroid gland to become more active and release excess amounts of thyroid hormone into the blood. A TSI test measures the amount of thyroid stimulating imm

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Vascular Endothelial Growth Factor (VEGF)

What is the VEGF test? This test measures the amount of vascular endothelial growth factor (VEGF) in your blood. VEGF is a substance that helps encourage the growth of new blood vessels. Your body makes more VEGF in certain cases. For instance, if

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Z SCORE (FEMALE)

A Z-score compares your bone density to the average bone density of people your own age and gender. For example, if you are a 50-year-old female, a Z-score compares your bone density to the average bone density of 50-year-old females.

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Z SCORE (MALE)

A Z-score compares your bone density to the average bone density of people your own age and gender. For example, if you are a 50-year-old female, a Z-score compares your bone density to the average bone density of 50-year-old females.

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