Small Intestinal Bacterial Overgrowth (SIBO) 3 Hour


Performed by: Genova Diagnostics

Biomarkers included in this panel:

Hydrogen (H2)

Hydrogen increase over baseline by 90 minutes. A rise of ≥ 20 ppm from baseline in hydrogen by 90 min should be considered a positive test to suggest the presence of SIBO

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Methane (CH4)

Utilization of breath methane levels for SIBO assessment is controversial largely due to a lack of validation related to diagnostic specifics such as timing and magnitude of increase; however, CH4 measurements are increasingly obtained to address oth

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Peak Combined Gas Production

A combined H2 + CH4 increase of 12 ppm or more may be suggestive of small intestinal bacterial overgrowth. Breath analysis standards for abnormal tests are suggested if an increase of 12ppm for Hydrogen (H2), 12ppm for Methane (CH4), or a combined

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