Epstein-Barr virus (EBV)

To help diagnose infectious mononucleosis (mono); to distinguish between an Epstein-Barr virus (EBV) infection and another illness with similar symptoms.

Please refer to this interpretation chart:

VCA IgG VCA IgM EBNA IgG Interpretation
Negative Negative Negative No previous exposure
Positive Positive Negative Recent infection
Positive Negative Positive Past infection
Positive Negative Negative See note*
Positive Positive Positive Past infection

 

Note:

*Results indicate infection with EBV at some time (VCA IgG positive). However, the time of the infection cannot be predicted (ie, recent or past) since antibodies to EBNA usually develop after primary infection (recent) or, alternatively, approximately 5% to 10% of patients with EBV never develop antibodies to EBNA (past).

EBNA Ab/IgG

Optimal range: 0 - 18 U/mL

The EBV (Epstein Barr) Nuclear Antigen Antibodies, IgG test looks for a type of antibody which the body typically develops in response to Epstein-Barr Virus.

EBNA antibodies usually appear 2-4 months after infection and persist for the life of the person.

This test is usually performed to establish a past infection with EBV.

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EBV Ab VCA, IgG

Optimal range: 0 - 18 U/mL

EBV-VCA, IgG is an antibody (protein) that is produced by the body in an immune response to an Epstein-Barr virus antigen.

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EBV Ab VCA, IgM

Optimal range: 0 - 36 U/mL

EBV-VCA, IgM is an antibody (protein) that is produced by the body in an immune response to an Epstein-Barr virus antigen.

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EBV CAPSID Ag.ab/IgG

Optimal range: 0 - 18 U/mL

EBV CAPSID Ag.ab/IgG is an antibody (protein) that is produced by the body in an immune response to an Epstein-Barr virus antigen.

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EBV CAPSID Ag.Ab/IgM

Optimal range: 0 - 36 U/mL

EBV CAPSID Ag.Ab/IgM is an antibody (protein) that is produced by the body in an immune response to an Epstein-Barr virus antigen.

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EBV EARLY Ag.Ab

Optimal range: 0 - 9 U/mL

Aid in the diagnosis of acute EBV (infectious mononucleosis) and EBV reactivation in conjunction with other serologic tests. The appearance of IgG antibodies to Early antigen-diffuse [EA(D)] is generally associated with the primary (acute) stage of EBV infection. For most individuals these antibodies are transient and are often undetectable after 6 months.

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EBV Early Antigen Ab, IgG

Optimal range: 0 - 9 U/mL

Aid in the diagnosis of acute EBV (infectious mononucleosis) and EBV reactivation in conjunction with other serologic tests. The appearance of IgG antibodies to Early antigen-diffuse [EA(D)] is generally associated with the primary (acute) stage of EBV infection. For most individuals these antibodies are transient and are often undetectable after 6 months.

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EBV Nuclear Antigen Ab, IgG

Optimal range: 0 - 17.9 U/mL

The EBV (Epstein Barr) Nuclear Antigen Antibodies, IgG test looks for a type of antibody which the body typically develops in response to Epstein-Barr Virus.

EBNA antibodies usually appear 2-4 months after infection and persist for the life of the person.  This test is usually performed to establish a past infection with EBV.

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Epstein Barr Virus (EBNA) AB (IGG)

Optimal range: 0 - 0.9 index

The EBV (Epstein Barr) Nuclear Antigen Antibodies, IgG test looks for a type of antibody which the body typically develops in response to Epstein-Barr Virus.

EBNA antibodies usually appear 2-4 months after infection and persist for the life of the person.

This test is usually performed to establish a past infection with EBV.

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Epstein Barr Virus VCA AB (IGG)

Optimal range: 0 - 0.9 index

EBV-VCA, IgG is an antibody (protein) that is produced by the body in an immune response to an Epstein-Barr virus antigen.

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Epstein Barr Virus VCA AB (IGM)

Optimal range: 0 - 0.9 index

EBV-VCA, IgM is an antibody (protein) that is produced by the body in an immune response to an Epstein-Barr virus antigen.

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Monospot Heterophile antibody

Optimal range: 0 - 0.001 index

The mononuclear spot test or monospot test, a form of the heterophile antibody test, is a rapid test for infectious mononucleosis due to Epstein–Barr virus (EBV).

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