Porphyrins, Quantitative, Random UrineUrine
Performed by: LabCorp
Urine porphyrins are useful for the evaluation of cutaneous (=relating to or affecting the skin) photosensitivity to exclude porphyria cutanea tarda (PCT).
Porphyria cutanea tarda (PCT) is a part of a spectrum of diseases that arise as a result of abnormal enzymes in the biosynthesis of heme. It is caused by the deficiency of the uroporphyrinogen III decarboxylase (UROD) enzyme and should be differentiated from other porphyrias.
Evaluation of neurologic and/or psychiatric symptoms associated with acute porphyrias (=a group of rare disorders characterized by an enzymatic defect in the heme biosynthetic pathway), such as acute intermittent porphyria (AIP), requires urine porphobilinogen (PBG) testing.
Biomarkers included in this panel:
Coproporphyrin (CP) I
Coproporphyrin I is a porphyrin metabolite arising from heme synthesis.Learn more
Coproporphyrin (CP) III
Coproporphyrin III is a porphyrin derivative. Small amounts of porphyrins (coproporphyrin) are excreted in normal human urine. Coproporphyrin also is present in bile and feces.Learn more
Heptacarboxyporphyrin is a Porphyrin. Porphyrins are precursors of heme and usually only occur in urine in negligible amounts.Learn more
Hexacarboxyporphyrin is a Porphyrin. Porphyrins are precursors of heme and usually only occur in urine in negligible amounts.Learn more
Porphyrins are a group of compounds defined by their chemical structure. These compounds are by-products of heme synthesis and are normally present at low levels in blood and other body fluids. Porphyrin tests measure porphyrins and their precursorsLearn more