Total Tox-Burden
Urine
Performed by: Vibrant Wellness
The Total Tox-Burden panel combines the Environmental Toxins, Mycotoxins, and Heavy Metals tests to measure a variety of toxins.
The Vibrant Mycotoxins test is a urine-based assay for 31 of the most common mycotoxins produced by molds to which humans are exposed. This test is measured on mass spectrometry, using Vibrant’s patent-pending proprietary technology, to produce the most accurate and clinically relevant assessment of difficult-to-detect toxins that can cause serious disease in humans. Vibrant is able to detect mycotoxins, small molecules, as small as 5 pcg, which greatly expands the number of available mycotoxins detected.
The Vibrant Heavy Metals test is a urine-based test to screen for 20 of the most common heavy metals known to accumulate and cause adverse health effects in the human body. This test can be taken either provoked or non-provoked.
Vibrant Environmental Toxin Panel uses the most advanced mass spectrometry method to assess 39 different markers to assess environmental toxins in one urine specimen.
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Biomarkers included in this panel:
DDT, a persistent organic pollutant once commonly used as a pesticide for controlling malaria and typhus, metabolizes in humans to produce 2,2-bis (4-chlorophenyl) acetic acid (DDA), the primary urinary metabolite and potential exposure biomarker. DD
Learn more2,3,4-Methylhippuric Acid (2,3,4-MHA) is a metabolite of xylene, a solvent commonly used in industrial and commercial products like paints, varnishes, adhesives, and gasoline. Elevated levels of 2,3,4-MHA in urine typically indicate significant expos
Learn more2-Hydroxyisobutyric acid is formed endogenously as a product of branched-chain amino acid degradation and ketogenesis. This compound is also the major metabolite of gasoline octane enhancers such as MTBE and ETBE. MTBE and ETBE are gasoline additi
Learn more3-Phenoxybenzoic Acid (3PBA) is a metabolite formed as a result of exposure to pyrethroids, a class of insecticides widely used in both household and agricultural settings. Pyrethroids account for approximately 30% of the insecticide market worldwide
Learn more4-Nonylphenols are used in manufacturing antioxidants, lubricating oil additives, laundry and dish detergents, emulsiers, and solubilizers. These compounds are also precursors used to produce paints, pesticides, cosmetics, and plastics. Nonylphenol p
Learn moreAflatoxin B1 (AFB1) is a mycotoxin produced by several strains of the fungus Aspergillus flavus. It is found in foods, specifically cereals such as corn and rice, tree nuts, oilseeds (peanut, cottonseed, etc.) and spices, notably those grown in tropi
Learn moreAatoxin B2 (AFB2) is a mycotoxin produced by several Aspergillus spp. and found in contaminated foods or hay exposed to water or humid conditions. Exposure routes are primarily ingestion or inhalation. Ingestion can either occur directly from food su
Learn moreAflatoxin G2 is a mycotoxin produced by certain species of molds, particularly Aspergillus flavus and Aspergillus parasiticus. This toxin is a member of the aflatoxin family, known for its potent carcinogenic and toxic effects on humans and animals.
Learn moreSOURCES: Found naturally in the environment, air, soil, water. Found in lead storage batteries, solder, sheet and pipe metal, pewter, bearings and castings, paints, ceramics, fireworks, plastic enamels, metal and glass. Sometimes used medica
Learn moreAtrazine is a common herbicide used in agriculture to control weeds. When it's used, it can break down in the environment into different forms, one of which is atrazine mercapturate. Atrazine and its breakdown products have been linked to potenti
Learn moreBeryllium is a silvery-white metal that is lighter than aluminum but stronger than steel. Its strength-to-weight ratio, reflectivity, transparency to X-rays, thermal stability and conductivity, and high melting point makes it an essential material in
Learn moreBisphenol A (BPA) is a xenoestrogen, exhibiting estrogen-mimicking, hormone-like properties that raise concern about its suitability in some consumer products and food containers. Bisphenol A (BPA) is an organic synthetic compound and it is a startin
Learn moreBisphenol S (BPS) is a synthetic compound used in the manufacturing of plastics and resins, commonly found in a wide range of consumer products, such as food and drink containers, water bottles, thermal receipt papers, dental sealants, toys, cosmetic
Learn moreButylparaben belongs to the paraben family and is one of the most common antimicrobial preservatives in cosmetics such as such as makeup, moisturizers, hair-care products, and shaving creams. It is also used in medication suspensions, and as a avorin
Learn moreSOURCES: Found in food such as shellfish, leafy vegetables, rice, cereals, cocoa butter, dried seaweed, and legumes. Also present in nickel cadmium batteries, cigarette smoke (including second-hand smoke), insecticides, fertilizer, motor oil, emis
Learn moreCesium is a naturally occurring element found combined with other elements in rocks, soil, and dust in low amounts. It is used to make atomic clocks, optical glass, and vacuum tubes. Nuclear explosions or the breakdown of uranium in fuel elements can
Learn moreChaetoglobosin A (CHA) is one of the chaetoglobosin mycotoxins produced from the fungus Chaetomium globosum. Chaetomium globosum is the third most common indoor fungal contaminant of damp buildings. It has been isolated from several places such as so
Learn moreCitrinin (CTN) is a mycotoxin that can be detected in a urine test, and its presence often signifies potential exposure to this fungal toxin. Citrinin is primarily produced by various species of molds, particularly Penicillium and Aspergillus, common
Learn moreDiethyldithiophosphate (DEDTP) is a metabolite of organophosphates, which are one of the most common causes of poisoning worldwide and are frequently intentionally used as pesticides. They can enter the body through the lungs or skin, or by eating co
Learn moreDiethylphosphate (DEP) is a metabolite of organophosphate pesticides, which are commonly used in agriculture to control pests and in residential environments to manage insects and rodents. Organophosphates exert their effects by inhibiting acetylchol
Learn moreDihydrocitrinone (DHC) is a metabolite of Citrinin (CTN), which is a mycotoxin produced by several fungal strains in the Penicillium, Aspergillus and Monascus genera and found in stored grains and other food products. Citrinin has nephrotoxic and gen
Learn moreOrganophosphates are one of the most toxic groups of substances in the world, primarily found in pesticide formulations. They are inhibitors of cholinesterase enzymes, leading to overstimulation of nerve cells, causing sweating, salivation, diarrhea,
Learn moreDimethylthiophosphate (DMTP) is a metabolite of organophosphates, which are among the most common causes of poisoning worldwide. Organophosphates are frequently used as pesticides and can enter the body through the lungs, skin, or by consuming contam
Learn moreDiphenyl phosphate (DPP) is a metabolite produced from exposure to triphenyl phosphate (TPHP), a chemical commonly used as a flame retardant in consumer products like furniture, electronics, and textiles. It is also found in personal care products su
Learn moreUrinary gadolinium (Gd) provides an indication of recent or ongoing exposure to the metal, and endogenous detoxification to a lesser extent. Urinary Gd would be expected to be variably high if urine was collected within a week of medicinal Gd adminis
Learn moreGlyphosate is the world's most widely produced herbicide. It is a broad-spectrum herbicide that is used in more than 700 different products for agriculture and forestry to home use. Possible treatment options if in higher ranges: Treatment
Learn moreThe fungicide/pesticide use of mercury has declined due to environmental concerns, but mercury residues persist in the environment. Emissions from coalfired power plants and hospital/municipal incinerators are significant sources of mercury pollution
Learn moreMethylparaben belongs to the paraben family and is an anti-fungal agent often used in a variety of cosmetics and personal-care products. It is also used as a food preservative. Methylparaben is generally recognized as safe for food and cosmetic antib
Learn moreMono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) is a metabolite of mono(2-ethylhexyl) phthalate (MEHP), which is part of the common environmental toxins known as phthalates. Phthalates, often referred to as plasticizers, are a group of chemicals used
Learn moreMono-(2-ethyl-5-oxohexyl) phthalate (MEOHP) is a metabolite of di-2-ethylhexyl phthalate (DEHP), a commonly used plasticizer in the manufacturing of flexible plastics. DEHP is widely found in products like PVC flooring, medical devices, and children&
Learn moreMono-(2-ethyl-5-oxohexyl) phthalate (MEOHP) is a metabolite of mono(2-ethylhexyl) phthalate (MEHP), which belongs to a group of common environmental toxins known as phthalates. Phthalates, also referred to as plasticizers, are chemicals used to make
Learn moreMono-2ethylhexyl phthalate (MEHP) is a metabolite of di(2-ethylhexyl) phthalate (DEHP), a common plasticizer used in a variety of consumer products, such as vinyl flooring, medical devices, and personal care items. MEHP is primarily detected through
Learn moreMonobutyl phthalate (MBP) is a metabolite of butyl phthalate, which is commonly used as a plasticizer in various consumer products, including plastics, cosmetics, and personal care items. When ingested or absorbed into the body, butyl phthalate break
Learn moreMonoethylphthalate (MEP) is a metabolite of the widely used chemical compound diethylphthalate (DEP), which is found in many consumer products, including personal care items, plastic products, and fragrances. As a breakdown product of DEP, MEP is com
Learn moreMonoisobutyl phthalate (MiBP) is a metabolite of dibutyl phthalate (DBP), a widely used plasticizer found in various consumer products. MiBP is often measured in toxicology panels, such as the ToxDetect panel, to assess potential exposure to phthalat
Learn moreMycophenolic Acid is an antifungal, antibacterial, and antiviral mycotoxin acid. It is produced by the Penicillium fungus. Mycophenolic Acid is an immunosuppressant which inhibits the proliferation of B and T lymphocytes. Mycophenolic Acid e
Learn moreN-Acetyl (2, hydroxypropyl) Cysteine (NAHP) is a metabolite of propylene oxide, which is majorly used to produce polyurethane plastics and fumigant. These materials are used in polyester resins for the textile and construction industries as well as f
Learn moreN-Acetyl (2-Cyanoethyl) Cysteine (NACE) is a metabolite formed as a result of exposure to acrylonitrile, a chemical found in a variety of products, including acrylic fiber clothing, carpeting, acrylonitrile-based plastics, and plastic food containers
Learn moreN-Acetyl (3,4-Dihydroxybutyl) Cysteine (NADB) is a metabolite produced as a result of exposure to 1,3-butadiene, a petrochemical primarily used in the production of synthetic rubber, including materials for car and truck tires. It is also an environm
Learn moreN-Acetyl (Carbomethyl) Cysteine is a metabolite formed as a result of exposure to acrylamide, a chemical that is produced when starchy foods like potatoes, grains, and coffee beans are cooked at high temperatures. Other sources of acrylamide exposure
Learn moreNAPR is a metabolite of 1-bromopropane. Chronic exposure can lead to decreased cognitive function and impairment of the central nervous system. Acute exposure can lead to headaches. 1-bromopropane is an organic solvent used for metal cleanin
Learn moreN-acetyl phenyl cysteine (NAP) is a metabolite derived from benzene, a chemical that has been widely used in the past as an industrial solvent. Due to its toxicity and associated health risks, the use of benzene has been significantly reduced. Howeve
Learn moreOchratoxin A (OTA), a renal toxin, is produced majorly by Aspergillus and Penicillium fungal species. Ochratoxin A has been found in barley, oats, rye, wheat, coffee beans, and other plant products, with barley having a particularly high likelihood o
Learn morePerchlorate (PERC) is a naturally occurring and man-made anion and is a powerful oxidizing agent. It is mainly used for propellants in rocket fuel as well as control static electricity in food packaging. Perchlorate may be accumulated into vegetables
Learn morePeruoropentanoate (PFPeA) is a short chain peruoroalkyl acid and used to make various products resistant to oil, stains, grease, and water. PFPeA is ubiquitous in the environment and is spread through water, food, and vehicles. Extensive public healt
Learn moreStyrene is used in the manufacturing of plastics, in building materials, and is found in car exhaust fumes. Polystyrene and its copolymers are widely used as food-packaging materials. The ability of styrene monomer to leach from polystyrene packaging
Learn moreSOURCES: Fish, shellfish, plants, cigarettes, soil, air, water, electronic devices, switches and closures for the semi-conductor industry, glass for medical procedures. NUTRIENT INTERACTIONS: Some of its toxic effects results from interferen
Learn moreTriclosan (TCS) is an antibacterial and antifungal agent found in various consumer products, such as toothpaste, soaps, detergents, toys, and surgical cleaning treatments. Humans are exposed to triclosan through skin absorption during activities like
Learn moreZearalenone (ZEN), a potent mycotoxin commonly found in contaminated crops, is increasingly recognized as a critical marker in Total Tox Burden panels due to its significant impact on health. Produced primarily by Fusarium species of fungi, ZEN is of
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