Total Tox-Burden


Performed by: Vibrant Wellness

Biomarkers included in this panel:

2,2-bis(4-Chlorophenyl) acetic acid (DDA)

2-Hydroxyisobutyric Acid (2HIB)

2-Hydroxyisobutyric acid is formed endogenously as a product of branched-chain amino acid degradation and ketogenesis. This compound is also the major metabolite of gasoline octane enhancers such as MTBE and ETBE. MTBE and ETBE are gasoline additi

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4-Nonylphenols are used in manufacturing antioxidants, lubricating oil additives, laundry and dish detergents, emulsiers, and solubilizers. These compounds are also precursors used to produce paints, pesticides, cosmetics, and plastics. Nonylphenol p

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Aflatoxin B1 (AFB1)

Aflatoxin B1 (AFB1) is a mycotoxin produced by several strains of the fungus Aspergillus flavus. It is found in foods, specifically cereals such as corn and rice, tree nuts, oilseeds (peanut, cottonseed, etc.) and spices, notably those grown in tropi

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Aflatoxin B2 (AFB2)

Aatoxin B2 (AFB2) is a mycotoxin produced by several Aspergillus spp. and found in contaminated foods or hay exposed to water or humid conditions. Exposure routes are primarily ingestion or inhalation. Ingestion can either occur directly from food su

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Aflatoxin G2

Aflatoxin G2 is a mycotoxin produced by certain species of molds, particularly Aspergillus flavus and Aspergillus parasiticus. This toxin is a member of the aflatoxin family, known for its potent carcinogenic and toxic effects on humans and animals.

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SOURCES: Found naturally in the environment, air, soil, water. Found in lead storage batteries, solder, sheet and pipe metal, pewter, bearings and castings, paints, ceramics, fireworks, plastic enamels, metal and glass. Sometimes used medica

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Atrazine mercapturate

Atrazine is a common herbicide used in agriculture to control weeds. When it's used, it can break down in the environment into different forms, one of which is atrazine mercapturate. Atrazine and its breakdown products have been linked to potenti

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Beryllium is a silvery-white metal that is lighter than aluminum but stronger than steel. Its strength-to-weight ratio, reflectivity, transparency to X-rays, thermal stability and conductivity, and high melting point makes it an essential material in

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Bisphenol A (BPA)

Bisphenol A (BPA) is a xenoestrogen, exhibiting estrogen-mimicking, hormone-like properties that raise concern about its suitability in some consumer products and food containers. Bisphenol A (BPA) is an organic synthetic compound and it is a startin

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Butylparaben belongs to the paraben family and is one of the most common antimicrobial preservatives in cosmetics such as such as makeup, moisturizers, hair-care products, and shaving creams. It is also used in medication suspensions, and as a avorin

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SOURCES: Found in food such as shellfish, leafy vegetables, rice, cereals, cocoa butter, dried seaweed, and legumes. Also present in nickel cadmium batteries, cigarette smoke (including second-hand smoke), insecticides, fertilizer, motor oil, emis

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Cesium is a naturally occurring element found combined with other elements in rocks, soil, and dust in low amounts. It is used to make atomic clocks, optical glass, and vacuum tubes. Nuclear explosions or the breakdown of uranium in fuel elements can

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Chaetoglobosin A (CHA)

Chaetoglobosin A (CHA) is one of the chaetoglobosin mycotoxins produced from the fungus Chaetomium globosum. Chaetomium globosum is the third most common indoor fungal contaminant of damp buildings. It has been isolated from several places such as so

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Citrinin (CTN)

Citrinin (CTN) is a mycotoxin that can be detected in a urine test, and its presence often signifies potential exposure to this fungal toxin. Citrinin is primarily produced by various species of molds, particularly Penicillium and Aspergillus, common

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Diethyldithiophosphate (DEDTP)

Diethyldithiophosphate (DEDTP) is a metabolite of organophosphates, which are one of the most common causes of poisoning worldwide and are frequently intentionally used as pesticides. They can enter the body through the lungs or skin, or by eating co

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Dihydrocitrinone (DHC) is a metabolite of Citrinin (CTN), which is a mycotoxin produced by several fungal strains in the Penicillium, Aspergillus and Monascus genera and found in stored grains and other food products. Citrinin has nephrotoxic and gen

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Dimethyl phosphate (DMP)

Organophosphates are one of the most toxic groups of substances in the world, primarily found in pesticide formulations. They are inhibitors of cholinesterase enzymes, leading to overstimulation of nerve cells, causing sweating, salivation, diarrhea,

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Urinary gadolinium (Gd) provides an indication of recent or ongoing exposure to the metal, and endogenous detoxification to a lesser extent. Urinary Gd would be expected to be variably high if urine was collected within a week of medicinal Gd adminis

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Glyphosate is the world's most widely produced herbicide. It is a broad-spectrum herbicide that is used in more than 700 different products for agriculture and forestry to home use. Possible treatment options if in higher ranges: Treatment

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The fungicide/pesticide use of mercury has declined due to environmental concerns, but mercury residues persist in the environment. Emissions from coalfired power plants and hospital/municipal incinerators are significant sources of mercury pollution

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Methylparaben belongs to the paraben family and is an anti-fungal agent often used in a variety of cosmetics and personal-care products. It is also used as a food preservative. Methylparaben is generally recognized as safe for food and cosmetic antib

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Mycophenolic Acid

Mycophenolic Acid is an antifungal, antibacterial, and antiviral mycotoxin acid. It is produced by the Penicillium fungus.  Mycophenolic Acid is an immunosuppressant which inhibits the proliferation of B and T lymphocytes. Mycophenolic Acid e

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N-Acetyl (2,Hydroxypropyl) Cysteine (NAHP)

N-Acetyl (2, hydroxypropyl) Cysteine (NAHP) is a metabolite of propylene oxide, which is majorly used to produce polyurethane plastics and fumigant. These materials are used in polyester resins for the textile and construction industries as well as f

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N-Acetyl (Propyl) Cysteine (NAPR)

NAPR is a metabolite of 1-bromopropane. Chronic exposure can lead to decreased cognitive function and impairment of the central nervous system.  Acute exposure can lead to headaches. 1-bromopropane is an organic solvent used for metal cleanin

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Ochratoxin A (OTA)

Ochratoxin A (OTA), a renal toxin, is produced majorly by Aspergillus and Penicillium fungal species. Ochratoxin A has been found in barley, oats, rye, wheat, coffee beans, and other plant products, with barley having a particularly high likelihood o

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Perchlorate (PERC)

Perchlorate (PERC) is a naturally occurring and man-made anion and is a powerful oxidizing agent. It is mainly used for propellants in rocket fuel as well as control static electricity in food packaging. Perchlorate may be accumulated into vegetables

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Perfluoroheptanoic acid (PFHpA)

Perfluoropentanoic acid (PFPeA)

Peruoropentanoate (PFPeA) is a short chain peruoroalkyl acid and used to make various products resistant to oil, stains, grease, and water. PFPeA is ubiquitous in the environment and is spread through water, food, and vehicles. Extensive public healt

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Perfluoroundecanoic acid (PFUnA)

Phenyl glyoxylic Acid (PGO)

Styrene is used in the manufacturing of plastics, in building materials, and is found in car exhaust fumes. Polystyrene and its copolymers are widely used as food-packaging materials. The ability of styrene monomer to leach from polystyrene packaging

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SOURCES: Fish, shellfish, plants, cigarettes, soil, air, water, electronic devices, switches and closures for the semi-conductor industry, glass for medical procedures. NUTRIENT INTERACTIONS: Some of its toxic effects results from interferen

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Zearalenone (ZEN)

Zearalenone (ZEN), a potent mycotoxin commonly found in contaminated crops, is increasingly recognized as a critical marker in Total Tox Burden panels due to its significant impact on health. Produced primarily by Fusarium species of fungi, ZEN is of

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