Organic Acids (VibrantWellness)

- Organic acids panels test for the organic acids in urine that are byproducts of daily cellular metabolism

- Based on known metabolic pathways and enzyme-cofactor requirements, these organic acid markers can provide great insights in discovering underlying causes of chronic symptoms

- Organic acids testing can aid advanced providers in the detection of imbalances, toxicity, and inflammation in chronically or acutely ill patients with complex illnesses

- Alongside other diagnostic testing, organic acids profiles complete the clinical picture of root causes and guide practitioners in developing the most individual and effective interventions

2-Hydroxyisocaproic acid

Optimal range: 0 - 0.88 mmol/mol

2-Hydroxyisocaproic acid (aka Leucic acid / α-hydroxyisocaproic acid / HICA) is a metabolite of the branched-chain amino acid leucine.

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Arabinose

Optimal range: 0 - 30 mmol/mol

Breakdown product of hyaluronic acid; also found in certain foods.

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Ascorbic acid (Vitamin C)

Optimal range: 12.2 - 179.25 mmol/mol

Ascorbic Acid is a natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibrous tissue, teeth, bones, connective tissue, skin, and capillaries.

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Citric acid

Optimal range: 0 - 498.8 mmol/mol

Citric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells. 

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Furancarbonylglycine

Optimal range: 0 - 1.82 mmol/mol

Furancarbonylglycine is a metabolite produced by Aspergillus and possibly other fungal species in the GI tract.

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HVA/DOPAC

Optimal range: 2.6 - 8.3 Ratio

HVA and DOPAC are the major metabolites of dopamine. HVA stands for Homovanillic acid and DOPAC stands for Dihydroxyphenylacetic.

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HVA/VMA Ratio

Optimal range: 0.74 - 1.88 Ratio

The Organic Acids Test measures levels of HVA (homovanillic acid) and VMA (vanillylmandelic acid), the metabolites of the neurotransmitters, dopamine and epinephrine/norepinephrine. It also measures the ratio of the two metabolites.

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Quinolinic acid/5-HIAA

Optimal range: 0.32 - 1.1 Ratio

A high ratio of quinolinic acid to the tryptophan metabolite, 5-hydroxyindoleacetic acid, indicates excessive inflammation due to recurrent infections, excessive tryptophan intake, immune overstimulation, excessive adrenal production of cortisol, or excessive exposure to phthalates.

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