IgG Subclass Deficiency

Antibodies are also called immunoglobulins. There are five types or classes of immunoglobulin: IgG, IgA, IgM, IgD and IgE. Most of the antibodies in the blood and the fluid that surround the tissues and cells of the body are of the IgG class. The IgG class of antibodies is composed of four different subtypes of IgG molecules called the IgG subclasses. These are designated IgG1, IgG2, IgG3 and IgG4. 

IgG, Subclass 1

Optimal range: 422 - 1292 mg/dL

IgG is a combination of four slightly different types of IgG called IgG subclasses: IgG1, IgG2, IgG3 and IgG4. When one or more of these subclasses is persistently low and total IgG is normal, a subclass deficiency is present.

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IgG, Subclass 2

Optimal range: 117 - 747 mg/dL

IgG is a combination of four slightly different types of IgG called IgG subclasses: IgG1, IgG2, IgG3 and IgG4. When one or more of these subclasses is persistently low and total IgG is normal, a subclass deficiency is present.

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IgG, Subclass 3

Optimal range: 41 - 129 mg/dL

IgG is a combination of four slightly different types of IgG called IgG subclasses: IgG1, IgG2, IgG3 and IgG4. When one or more of these subclasses is persistently low and total IgG is normal, a subclass deficiency is present.

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IgG, Subclass 4

Optimal range: 1 - 291 mg/dL

IgG is a combination of four slightly different types of IgG called IgG subclasses: IgG1, IgG2, IgG3 and IgG4. When one or more of these subclasses is persistently low and total IgG is normal, a subclass deficiency is present.

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