ANA 12 Plus Profile (RDL)

Serum

Performed by: LabCorp

Biomarkers included in this panel:

Anti-Cardiolipin Ab, IgA (RDL)

Serum

Anti-Cardiolipin antibodies (aCL) of the IgA class are autoantibodies that target cardiolipin, a phospholipid found in cell membranes. While less commonly discussed than their IgG and IgM counterparts, IgA anti-cardiolipin antibodies also play a role

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Anti-Cardiolipin Ab, IgG (RDL)

Serum

Anti-Cardiolipin antibodies (aCL) of the IgG class are a type of autoantibody directed against cardiolipin, a phospholipid present in cell membranes. These antibodies are significant in the diagnosis and management of autoimmune disorders, particular

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Anti-Cardiolipin Ab, IgM (RDL)

Serum

Anti-Cardiolipin antibodies (aCL) of the IgM class are autoantibodies directed against cardiolipin, a specific phospholipid in cell membranes. These antibodies are clinically significant, especially in the context of antiphospholipid syndrome (APS),

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Anti-CCP Ab, IgG / IgA (RDL)

Serum

Anti-CCP antibodies, or anti-cyclic citrullinated peptide antibodies, are autoantibodies frequently found in the blood of individuals with rheumatoid arthritis (RA). These antibodies target proteins that have been altered by a process called citrulli

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Anti-Centromere Ab by IFA (RDL)

Serum

Anti-Chromatin Ab, IgG (RDL)

Serum

Anti-dsDNA Ab by Farr method (RDL)

Serum

The anti-double stranded DNA (anti-dsDNA) tests are used to help diagnose and monitor lupus, also called systemic lupus erythematosus or SLE, a chronic inflammatory autoimmune disorder in which the immune system mistakenly targets the body’s ow

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Anti-La (SS-B) Ab (RDL)

Serum

The Anti-La (SS-B) Antibody test is an important diagnostic tool for autoimmune disorders. This test specifically detects antibodies against the La (or SS-B) antigen, which is another key protein target in certain autoimmune diseases. The presence of

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Anti-Nuclear Ab by IFA (RDL)

Serum

Anti-Nuclear Antibody by IFA (RDL) refers to a diagnostic test that detects antinuclear antibodies (ANAs) in the blood. ANAs are a group of autoantibodies that target substances found in the nucleus of cells, and their presence is often associated wi

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Anti-Ro (SS-A) Ab (RDL)

Serum

The Anti-Ro (SS-A) Antibody test is a critical diagnostic tool in the assessment of autoimmune diseases. This test detects antibodies against the Ro/SS-A antigen, a protein implicated in the development of certain autoimmune conditions. The presence

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Anti-Scl-70 Ab (RDL)

Serum

Anti-Scl-70 antibodies, also known as Anti-Topoisomerase I antibodies, are a specific type of autoantibody primarily associated with systemic sclerosis (scleroderma), a chronic autoimmune disease. These antibodies target the enzyme topoisomerase I, w

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Anti-Sm Ab (RDL)

Serum

Anti-Sm antibodies (Anti-Smith antibodies) are autoantibodies that are strongly associated with systemic lupus erythematosus (SLE), a chronic autoimmune disease. The presence of Anti-Sm antibodies is considered a specific marker for SLE, as these ant

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Anti-TPO Ab (RDL)

Serum

Anti-TPO antibodies (Anti-Thyroid Peroxidase antibodies) are autoantibodies directed against thyroid peroxidase, an enzyme crucial for the production of thyroid hormones. These antibodies are a key marker in autoimmune thyroid diseases, particularly

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Anti-U1 RNP Ab (RDL)

Serum

The Anti-U1 RNP (Ribonucleoprotein) Antibody test is a specific diagnostic tool used in the evaluation of connective tissue diseases. This test detects antibodies against the U1 RNP, a component of a small nuclear ribonucleoprotein complex involved i

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C3 Complement (RDL)

Serum

C3 Complement, often simply referred to as C3, is a crucial protein component of the immune system's complement system. The complement system is a part of the innate immune response and plays a significant role in inflammation and defending again

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C4 Complement (RDL)

Serum

C4 Complement, an essential component of the immune system's complement pathway, plays a pivotal role in both innate and adaptive immunity. Similar to C3, C4 is involved in the activation of the complement system, particularly in the classical an

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Homogeneous Pattern

Serum

The Homogeneous pattern observed in an Antinuclear Antibody (ANA) test is a specific type of result that indicates the presence of antibodies in the blood that are reacting against components in the cell nucleus. This pattern is termed 'homogeneo

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Nuclear Dot Pattern

The Nuclear Dot Pattern, observed in Antinuclear Antibody (ANA) testing, is a distinctive immunofluorescence pattern characterized by discrete speckles or dots within the cell nucleus. This pattern emerges when specific autoantibodies in the patient&

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Rheumatoid Factor by Turb RDL

Serum

Speckled Pattern

The speckled pattern in ANA (Antinuclear Antibody) testing is one of the most common and diagnostically significant patterns, characterized by its distinctive, fine or coarse speckled appearance under a fluorescence microscope. This pattern indicates

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