Furancarbonylglycine is a metabolite that can be detected in an Organic Acid Test (OAT). It is produced by Aspergillus and possibly other fungal species that can colonize the gastrointestinal (GI) tract. Elevated levels of Furancarbonylglycine in the OAT results are often indicative of the presence of these fungi in the GI tract, specifically Aspergillus mold.
→ Metabolite of Fungal Growth: Furancarbonylglycine is a metabolic byproduct of fungal growth, particularly Aspergillus and potentially other fungal species.
→ GI Tract Colonization: Elevated levels of Furancarbonylglycine in the OAT may suggest the colonization of these fungi in the gastrointestinal tract.
→ Clinical Significance: This marker is clinically significant as it can indicate fungal overgrowth in the GI tract, which may be associated with various health issues and symptoms.
High levels of Furancarbonylglycine is often related to aspergillus and/or penicillium mold.
Treatment: Addressing elevated Furancarbonylglycine levels typically involves addressing fungal overgrowth through dietary changes, antifungal medications, and probiotics to restore a healthier microbial balance in the gut. The most common exposure source is moldy food, i.e. fruits, grains, cheese. After addressing dietary issues, these markers will often normalize upon retesting. At times environmental exposure is the source, i.e. mold damage in the home. Prescription or natural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth.
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