Pneumococcal Ab (23 Serotype)Serum
Performed by: LabCorp
This test measures IgG antibody levels to Streptococcus Pneumoniae to determine how well a person has responded to vaccination. Streptococcus Pneumoniae (pneumococcal) is a bacteria that is responsible for the majority of cases of pneumonia as well as other conditions including bronchitis, septicemia, and meningitis. Pneumonia is most dangerous for young children, people over the age of 65, or those with other conditions that are already weakening their immune system. Several types of pneumococcal vaccines are available. The 2 most common vaccines are Prevnar13 (PCV13) and Pneumovax23 (PPSV23). PCV13 provides protection from 13 pneumococcus serotypes and PPSV23 provides protection from 23 serotypes. Depending on a person's age and other risk factors, they may be recommended to take one or both vaccines. After being vaccinated, a blood test can help to verify that a person has developed sufficient levels of IgG antibodies to protect them from infection.
This test looks at antibodies to the same 23 serotypes which are included in the PPSV23 vaccine. The common numerical classification for these serotypes are 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F. IgG antibodies typically take 3-4 weeks after vaccination to fully develop.
Antibody testing is typically ordered after someone has completed taking the pneumococcus vaccine to verify that they have developed sufficient antibody levels for protection. The results of this test should be reviewed with a person's doctor.