DUTCH

The DUTCH test is a urine steroid hormone test that measures hormones and hormone metabolites from a dried urine sample.

16-OH-E1 (male)

Optimal range: 0 - 1.2 ng/mg

16α-Hydroxyestrone (16α-OH-E1), or hydroxyestrone, also known as estra-1,3,5(10)-trien-3,16α-diol-17-one, is an endogenous steroidal estrogen and a major metabolite of estrone, as well as an intermediate in the biosynthesis of estriol. 

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2-Methoxy-E1 (male)

Optimal range: 0 - 2.8 ng/mg

The 2-Methoxy Estrogens are considered to be protective. Low levels are usually a reflection of overall low estrogens and may be improved with supplemental estrogen.

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2-OH-E1 (male)

Optimal range: 0 - 5.9 ng/mg

2-Hydroxyestrone is an endogenous biomarker and major urinary metabolite of estrone and estradiol. Along with 16α-Hydroxyestrone, 2-Hydroxyestrone is used as an indicator for increased risk of cancer.

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4-OH-E1 (male)

Optimal range: 0 - 0.8 ng/mg

A very carcinogenic estrogen metabolite, levels low in the reference range are desirable. Additional magnesium, liver support, and methylation support may help decrease 4-OH-E1 levels.

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a-Pregnanediol (male)

Optimal range: 20 - 130 ng/mg

Progesterone itself is not readily found in the urine. Instead, this test measures pregnanediol (a progesterone metabolite). Pregnanediol is well-established in research literature as a reliable marker for progesterone levels.

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a-Pregnanediol (oral progesterone range)

Optimal range: 580 - 3000 ng/mg

This test measures pregnanediol, a metabolite of progesterone. It is used in the evaluation and decision making in women who are having difficulty becoming pregnant or maintaining a pregnancy. It is also used to monitor “high-risk” pregnancies.

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b-Pregnanediol (male)

Optimal range: 75 - 400 ng/mg

Progesterone itself is not readily found in the urine. Instead, this test measures pregnanediol (a progesterone metabolite). Pregnanediol is well-established in research literature as a reliable marker for progesterone levels.

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b-Pregnanediol (oral progesterone range)

Optimal range: 2000 - 9000 ng/mg

Pregnanediol is a metabolite of the molecule of progesterone, which is important for fertility and for menstruation. Pregnanediol levels increase after ovulation and when the placenta releases the hormone.

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Estradiol (E2) (male)

Optimal range: 0.5 - 2.2 ng/mg

Estradiol is the main "female" hormone. The full name is 17-beta-Estradiol.

Current research indicates that, in some people, this hormone may play a role in the loss of bone density, prevents male bodies from clearing DHT out of the prostate gland, and can stimulate estrogen-sensitive tumor growth (if estrogen-sensitive cancer cells are already present).

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Estriol (E3) (male)

Optimal range: 2 - 8 ng/mg

Has weak estrogen activity. Considered to be a protective estrogen. Most prevalent estrogen in pregnancy.

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Estrone(E1) (male)

Optimal range: 4 - 16 ng/mg

There are three types of estrogen: estradiol, estriol, and estrone. Estradiol is the primary female sex hormone. Estriol and estrone are minor female sex hormones. Estriol is nearly undetectable in women who aren’t pregnant.

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Progesterone

Optimal range: 6 - 20 ng/mL

Although Progesterone is found in both males and females, it is primarily known for its role in conception, pregnancy, and the regulation of a woman’s menstrual cycle.

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Total Estrogen (male)

Optimal range: 10 - 34 ng/mg

Estrogen is known as the “female” hormone. The four major naturally occurring estrogens in women are estrone (E1), estradiol (E2), estriol (E3), and estetrol (E4).

Although estrogen is identified with females, it is also found in men.

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