Chemical Immune Reactivity Screen (Cyrex Laboratories)

Array 11 measures an expanded range of environmental chemical toxins that bind to human tissues versus other laboratory tests that only identify chemical exposure.

Clinical Use:

- Identify the loss of immune tolerance associated with chemical exposure, which may lead to autoimmune reactivity

- Assist in setting guidelines for the avoidance of specific chemicals to reduce the risk of igniting the autoimmune process

- Monitor the effectiveness of the clinical management of patients

Aflatoxins IgG+IgA

Optimal range: 0.9 - 3.2 ELISA Index

Aflatoxins are organic chemical compounds produced by a polyketide pathway by many strains of the mold, Aspergillus.

Aspergillus flavus is a particular strain common contaminant in agricultural products such as peanuts, rice, figs and corn.

Aflatoxin B1 is the most potent natural carcinogen known and is usually the major aflatoxin produced by toxigenic strains. The Curse of the Mummy has been a popular theme for literature, films and folklore.

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Aflatoxins IgM

Optimal range: 0.4 - 2.3 ELISA Index

Aflatoxins are organic chemical compounds produced by a polyketide pathway by many strains of the mold, Aspergillus.

Aspergillus flavus is a particular strain common contaminant in agricultural products such as peanuts, rice, figs and corn.

Aflatoxin B1 is the most potent natural carcinogen known and is usually the major aflatoxin produced by toxigenic strains. The Curse of the Mummy has been a popular theme for literature, films and folklore.

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Benzene Ring Compounds IgG+IgA

Optimal range: 0.4 - 1.6 ELISA Index

Benzene Ring Compounds IgM

Optimal range: 0.3 - 2.1 ELISA Index

Benzene Ring Compounds: Benzene, Pheno, Toluene, Xylene

Classified as a hydrocarbon, Benzene [C6H6] is an organic chemical compound composed of 6 carbon atoms forming a hexagonal ring arrangement. Benzene is a solvent found in crude oil. Because it has a high octane number, it is utilized in gasoline. Benzene is also used as a precursor to heavy chemicals (i.e. ethylbenzene, cumene from which acetone and phenols are derived).

Most solvents are neurotoxic and many are carcinogenic.

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Bisphenol A IgG+IgA

Optimal range: 0.1 - 1.8 ELISA Index

Bisphenol A IgM

Optimal range: 0.1 - 2 ELISA Index

BPA Binding Protein IgG+IgA

Optimal range: 0.4 - 1.5 ELISA Index

BPA Binding Protein IgM

Optimal range: 0.2 - 1.2 ELISA Index

Formaldehyde and Glutaraldehyde IgG+IgA

Optimal range: 0.6 - 2.4 ELISA Index

Formaldehyde is an organic compound. Formaldehyde-based materials are common to the manufacture of automobiles. Formaldehyde-containing resins – melamine formaldehyde, ureaformaldehyde, phenolformaldehyde, carbamide formaldehyde – are used as a binder in plywood and particleboard production, home furnishings, household cleaners, paints, textiles, landscape and yard products, medicinal and personal care products, pesticides, fire retardation, increased water repellency, stiffness, carpeting made with synthetic fibers, and wrinkle-resistance in fabric finishing; paper products treated with formaldehyde include paper bags, waxed paper, paper towels, and disposable sanitary products; in the health care industry, formaldehyde is used in disinfectants, preservatives, and embalming fluid. Thus, formaldehyde exposure occurs in multiple home and work environments. Formaldehyde has been classified as a known human carcinogen by the International Agency for Research on Cancer.

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Formaldehyde and Glutaraldehyde IgM

Optimal range: 0.4 - 2.7 ELISA Index

Formaldehyde is an organic compound. Formaldehyde-based materials are common to the manufacture of automobiles. Formaldehyde-containing resins – melamine formaldehyde, ureaformaldehyde, phenolformaldehyde, carbamide formaldehyde – are used as a binder in plywood and particleboard production, home furnishings, household cleaners, paints, textiles, landscape and yard products, medicinal and personal care products, pesticides, fire retardation, increased water repellency, stiffness, carpeting made with synthetic fibers, and wrinkle-resistance in fabric finishing; paper products treated with formaldehyde include paper bags, waxed paper, paper towels, and disposable sanitary products; in the health care industry, formaldehyde is used in disinfectants, preservatives, and embalming fluid. Thus, formaldehyde exposure occurs in multiple home and work environments. Formaldehyde has been classified as a known human carcinogen by the International Agency for Research on Cancer.

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Isocyanate IgG+IgA

Optimal range: 0.2 - 1.5 ELISA Index

Isocyanates are a family of highly reactive, low molecular weight chemicals.

Exposure to toluene diisocyanate (TDI) and other isocyanates can cause irritation of the mucous membranes, eyes, upper respiratory tract, and skin.

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Isocyanate IgM

Optimal range: 0.2 - 2.1 ELISA Index

Isocyanates are a family of highly reactive, low molecular weight chemicals.

Exposure to toluene diisocyanate (TDI) and other isocyanates can cause irritation of the mucous membranes, eyes, upper respiratory tract, and skin.

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Mercury Compounds IgG+IgA

Optimal range: 0.2 - 1.3 ELISA Index

Mercury Compounds IgM

Optimal range: 0.1 - 2.2 ELISA Index

Mixed Heavy Metals IgG+IgA

Optimal range: 0.2 - 1.8 ELISA Index

Mixed Heavy Metals IgM

Optimal range: 0 - 2.1 ELISA Index

Parabens IgG+IgA

Optimal range: 0.2 - 1.5 ELISA Index

Parabens IgM

Optimal range: 0 - 1.2 ELISA Index

Tetrabromobisphenol A IgG+IgA

Optimal range: 0.3 - 1.4 ELISA Index

Tetrabromobisphenol A IgM

Optimal range: 0 - 2.5 ELISA Index

Tetrachloroethylene IgG+IgA

Optimal range: 0.1 - 1.5 ELISA Index

Tetrachloroethylene IgM

Optimal range: 0.1 - 2.1 ELISA Index

Trimellitic and Phthalic Anhydrides IgM

Optimal range: 0.4 - 2.6 ELISA Index
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