OMX Organic Metabolomics / Diagnostic Solutions
Advanced Organic Acids and Amino Acids Profile
Metabolomics, also called comprehensive metabolic profiling, evaluates patterns of metabolites related to core biological systems, offering insight into biochemical dysfunctions that may be of concern.
Organic acids and other small molecules are intermediate compounds that can define the efficient flow of pathways and substrates such as amino acids to reveal the level of inputs, which together establish the functional status of key areas of health.
Metabolites are impacted by many factors and can change in response to diet, nutrient status, toxin exposures, exercise, physiologic demands, genetics, gut microbiome alterations, or disease stage.
Metabolic analysis can help to evaluate the function of key pathways to better target support.
OMX Provides Insight Into the Following Areas of Health:
- Metabolic and macronutrient processing
- Nutritional and vitamin status
- Level and flow of amino acid
- Detoxification
- Mood issues
- Gut concerns
- Overall well-being
1-Methylhistidine
Optimal range: 88 - 394.4 nmol/mg Creatinine2-Methylhippuric Acid
Optimal range: 0 - 2.1 nmol/mg Creatinine2-Methylsuccinic Acid
Optimal range: 3.2 - 21.1 nmol/mg Creatinine3,4-Dihydroxyhydrocinnamic Acid
Optimal range: 0 - 1490.3 nmol/mg Creatinine3,5-Dihydroxybenzoic Acid
Optimal range: 0 - 277.1 nmol/mg Creatinine3-Methylhistidine
Optimal range: 49.7 - 1852.9 nmol/mg Creatinine
3-Methylhistidine is an amino acid which is excreted in human urine.
The measurement of 3-methylhistidine provides an index of the rate of muscle protein breakdown. 3-Methylhistidine is a biomarker for meat consumption, especially chicken. It is also a biomarker for the consumption of soy products.
LEARN MORE3-Phenylpropionylglycine
Optimal range: 0 - 1.3 nmol/mg Creatinine4-Hydroxybenzoic Acid
Optimal range: 0 - 14.9 nmol/mg Creatinine4-Hydroxyphenylacetic Acid
Optimal range: 85.8 - 902.3 nmol/mg Creatinine4-Hydroxyphenylpyruvic Acid
Optimal range: 35.5 - 1116.3 nmol/mg Creatinine5-Hydroxyindoleacetic Acid
Optimal range: 6.3 - 28.7 nmol/mg Creatinine8-Hydroxy-2'-deoxyguanosine
Optimal range: 0 - 8.4 nmol/mg Creatininea-Hydroxybutyric Acid
Optimal range: 10.6 - 62.6 nmol/mg Creatininea-Ketoglutaric Acid
Optimal range: 0 - 157.2 nmol/mg Creatininea-Ketoisovaleric Acid
Optimal range: 0 - 11.9 nmol/mg Creatininea-Aminoadipic Acid
Optimal range: 4.5 - 75.3 nmol/mg Creatininea-Keto-b-methylvaleric Acid
Optimal range: 0 - 11.9 nmol/mg Creatininea-Ketoglutaric Acid
Optimal range: 0 - 157.2 nmol/mg Creatininea-Ketoisocaproic Acid
Optimal range: 0 - 17 nmol/mg CreatinineAdipic Acid
Optimal range: 2 - 15.1 nmol/mg CreatinineAlanine
Optimal range: 65.4 - 572.6 nmol/mg CreatinineAnserine
Optimal range: 0 - 364.6 nmol/mg Creatinine
Anserine is part of a group of Beta-Amino Acids and Derivatives. Anserine is beta-alanyl-1-methyl-L-histidine, and it is known to come from chicken, turkey, duck, rabbit, tuna and salmon.
LEARN MOREAnthranilic Acid
Optimal range: 0 - 11.8 nmol/mg CreatinineArabinitol
Optimal range: 0 - 9 nmol/mg CreatinineArginine
Optimal range: 0 - 31.4 nmol/mg CreatinineArginosuccinic Acid
Optimal range: 0 - 49.7 nmol/mg CreatinineAsparagine
Optimal range: 30.6 - 199.2 nmol/mg CreatinineAspartic Acid
Optimal range: 0 - 51.1 nmol/mg Creatinineb-Hydroxybutyric Acid
Optimal range: 0 - 60.5 nmol/mg Creatinineb-Alanine
Optimal range: 0 - 11.8 nmol/mg Creatinineb-Hydroxyisovaleric Acid
Optimal range: 25.1 - 223.4 nmol/mg CreatinineBenzoic Acid
Optimal range: 0 - 488 nmol/mg CreatinineBenzoylform
Optimal range: 0 - 4.3 nmol/mg CreatinineBranched Chain Alpha-Keto Organic Acids
Optimal range: 0 - 28.3 nmol/mg CreatinineCarnosine
Optimal range: 3.9 - 70 nmol/mg Creatininecis-Aconitic Acid
Optimal range: 91.3 - 363.1 nmol/mg CreatinineCitric Acid
Optimal range: 356.2 - 2000 nmol/mg CreatinineCitrulline
Optimal range: 0 - 13.6 nmol/mg CreatinineCortisol
Optimal range: 0 - 82 nmol/mg CreatinineCreatinine
Optimal range: 29.3 - 296.8 nmol/mg CreatinineCystathionine
Optimal range: 3.6 - 85.5 nmol/mg CreatinineCystine
Optimal range: 9.7 - 96.1 nmol/mg CreatinineEquol
Optimal range: 0 - 12.8 nmol/mg CreatinineEthanolamine
Optimal range: 68 - 405 nmol/mg CreatinineEthylmalonic Acid
Optimal range: 5 - 43.3 nmol/mg CreatinineFormiminoglutamic Acid
Optimal range: 0 - 0.4 nmol/mg CreatinineFructose
Optimal range: 0 - 4.7 nmol/mg CreatinineFumaric Acid
Optimal range: 320.2 - 3375.5 nmol/mg Creatinine
Fumarate (together with Succinate and Malate) is used in the body’s metabolic pathway that generates cellular energy – the Citric Acid Cycle.
LEARN MOREg-Aminobutyric Acid
Optimal range: 0 - 0 nmol/mg CreatinineGlucaric Acid
Optimal range: 3.6 - 25.8 nmol/mg CreatinineGlucose
Optimal range: 0 - 15.2 mg/dLGlutamic Acid
Optimal range: 6.5 - 83.4 nmol/mg Creatinine
Glutamic acid (or Glutamate) is a major mediator of excitatory signals in the brain and is involved in most aspects of normal brain function including cognition, memory and learning.
LEARN MOREGlutamine
Optimal range: 126.4 - 659.1 nmol/mg CreatinineGlutamine / Glutamate Ratio
Optimal range: 2.5 - 39.5 nmol/mg Creatinine
- Glutamic acid has been associated with higher BMI, blood pressure, and insulin resistance, while glutamine levels were inversely associated.
- A high plasma glutamine-to-glutamic acid ratio was associated with lower risk of diabetes in the Framingham Heart Study (n=1015).
- Higher glutamine-to-glutamic acid ratio was associated with a better cardiometabolic-risk profile over 10 years in the PRIMED study (n=1879).
LEARN MOREGlutaric Acid
Optimal range: 0 - 4.5 nmol/mg CreatinineGlycine
Optimal range: 248.3 - 6396 nmol/mg CreatinineGlycylproline
Optimal range: 0 - 18.9 nmol/mg CreatinineHexanoylglycine
Optimal range: 0 - 2.6 nmol/mg CreatinineHippuric Acid
Optimal range: 0 - 291.9 nmol/mg CreatinineHistidine
Optimal range: 126.4 - 1592.8 nmol/mg CreatinineHomocitrulline
Optimal range: 6.1 - 43.5 nmol/mg CreatinineHomocystine
Optimal range: 0 - 5.7 nmol/mg CreatinineHomogentisic Acid
Optimal range: 7.9 - 336.4 nmol/mg CreatinineHomovanillic Acid
Optimal range: 0 - 10.3 nmol/mg CreatinineHydroxykynurenine
Optimal range: 0 - 12.1 nmol/mg CreatinineHydroxyproline
Optimal range: 0 - 25.3 nmol/mg CreatinineIndoleacetic Acid
Optimal range: 0 - 13.7 nmol/mg CreatinineIsocitric Acid
Optimal range: 0 - 415.6 nmol/mg CreatinineIsoleucine/allo-Isoleucine
Optimal range: 0 - 14.9 nmol/mg CreatinineKT Ratio
Optimal range: 0.064 - 0.638 nmol/mg CreatinineKynurenic Acid
Optimal range: 2.1 - 18.5 nmol/mg CreatinineKynurenine
Optimal range: 0 - 13.7 nmol/mg CreatinineLactic Acid
Optimal range: 23.1 - 722.6 nmol/mg CreatinineLeucine
Optimal range: 0 - 35.4 nmol/mg CreatinineLysine
Optimal range: 23.3 - 1800.4 nmol/mg CreatinineMalic Acid
Optimal range: 0 - 21.5 nmol/mg CreatinineMandelic Acid
Optimal range: 0 - 4.6 nmol/mg CreatinineMethionine
Optimal range: 0 - 11 nmol/mg CreatinineMethylmalonic Acid
Optimal range: 2.7 - 25.9 nmol/mg CreatinineMicroalbumin
Optimal range: 0 - 130.4 nmol/mg CreatinineOrnithine
Optimal range: 0 - 63 nmol/mg CreatinineOrotic Acid
Optimal range: 0.7 - 6 nmol/mg CreatinineOxalic Acid
Optimal range: 0 - 1532.5 nmol/mg CreatininePhenylacetic Acid
Optimal range: 0.5 - 19.1 nmol/mg CreatininePhenylalanine
Optimal range: 11.7 - 73.7 nmol/mg CreatininePhosphate
Optimal range: 11.2 - 192.4 nmol/mg CreatininePhosphoethanolamine
Optimal range: 0 - 49.7 nmol/mg CreatininePicolinic Acid
Optimal range: 0 - 4 nmol/mg CreatininePimelic Acid
Optimal range: 5.9 - 31.8 nmol/mg CreatinineProline
Optimal range: 0 - 14.7 nmol/mg CreatininePyridoxic Acid
Optimal range: 0 - 111.9 nmol/mg CreatininePyroglutamic Acid
Optimal range: 0 - 72.7 nmol/mg CreatininePyruvic Acid
Optimal range: 0 - 47.2 nmol/mg CreatinineQuercetin
Optimal range: 2.7 - 100 nmol/mg CreatinineQuinolinic Acid
Optimal range: 9 - 105.7 nmol/mg CreatinineSarcosine
Optimal range: 0 - 148.3 nmol/mg Creatinine
Sarcosine is also known as N-methylglycine. It is an intermediate and byproduct in the glycine synthesis and degradation. Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase, while glycine-N-methyl transferase generates sarcosine from glycine.
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