Hormone Report; saliva (Labrix, Doctor's Data)

This profile reports hormone levels. The Pg/E2 ratio assesses the relationship between estradiol, which can drive cellular proliferation, and progesterone, which mitigates that growth and potentiates cellular differentiation.

Hormones are powerful molecules essential for maintaining physical and mental health. We frequently think of estrogen as being a female hormone, and testosterone as being a male hormone. But men AND women make both, plus several more that need to be in balance for optimum health. An imbalance of any one hormone can throw your physical and mental health out of balance, causing aggravating and even serious health problems.

One size does not fit all when it comes to hormones. For decades western medicine has prescribed hormone replacement therapy as if everyone needed the same thing and the same amount. Nothing could be further from the truth. Your hormones are like your fingerprints and in order to achieve optimal health, you need to know what your specific imbalances are. Female and male hormone tests can help identify these imbalances.

There are several ways to test for hormones (saliva, serum and urine). Saliva is the best method to test the active/bioavailable portion of hormones, which are reflective of tissue levels.

Estradiol (E2)

Optimal range: 0.6 - 4.5 pg/mL

Estradiol (E2) is produced in women mainly in the ovary. The testes and adrenal glands are the principal source of estradiol in men. In women, normal levels of estradiol provide for proper ovulation, conception, and pregnancy, while also promoting healthy bone structure and regulating cholesterol levels.


Pg/E2 Ratio

Optimal range: 200 - 1000 Ratio

This ratio is helpful when both E2 and Pg are within range, yet the patient continues to have symptoms. It is not expected to be normal or used clinically when either E2 and/or Pg are outside of their expected ranges or if the patient does not have clinical symptoms.


Progesterone (Pg)

Optimal range: 127 - 446 pg/mL

Progesterone is a female sex hormone of primary importance in ovulation, fertility and menopause. It is particularly important in preparing the endometrium for the implantation of the blastocyte and in maintaining pregnancy. In the follicular phase of menstrual cycle progesterone is produced in low levels. It increases to the LH peak and then sharply rises to high levels. Next there is a sharp decline to low levels of follicular phase. In non-pregnant women progesterone is mainly secreted by the corpus luteum whereas in pregnancy the placenta becomes the major source. Minor sources for progesterone are the adrenal cortex for both sexes and the testes for males.



Optimal range: 6 - 49 pg/mL

Testosterone is an anabolic hormone produced predominately by the ovaries in women and the testes in men, and to a lesser extent in the adrenal glands. It is essential for creating energy,  maintaining optimal brain function (memory), regulating the immune
system, and building and maintaining the integrity of structural tissues such as skin, muscles, and bone. Premenopausal testosterone levels usually fall within the high-normal range and postmenopausal levels at low-normal range. In men testosterone levels peak in the teens and then fall throughout adulthood.