Branched Chain Amino Acids (Isoleucine, Leucine, Valine) are the three branched chain amino acids (BCAAs). Branched chain amino acids (BCAA) are essential amino acids and must be obtained from the diet (mainly meat, grains, and dairy).
Branched-Chain Amino Acids (BCAAs) are required for protein synthesis and are metabolized outside hepatic tissues, unlike most other essential amino acids. They are converted to branched-chain keto acids which require B-complex vitamins. BCAAs have been associated with obesity, weight loss, insulin resistance, and nonalcoholic fatty liver disease (NAFLD).
BCAA’s are nitrogen donors, facilitate glucose uptake by liver and skeletal muscle, and enhance glycogen synthesis.
- BMI was positively associated with urine 2-hydroxyisobutyrate, isoleucine, valine, tryptophan, and tyrosine.
- Elevated urine levels were associated with higher colorectal cancer.
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- BMI was positively associated with urine 2-hydroxyisobutyrate, isoleucine, valine, tryptophan, and tyrosine.
- Elevated urine levels were associated with higher colorectal cancer.
- High fasting levels may be caused by a deficiency of vitamin B6, elevated insulin levels, or excessive BCAA intake.
- Studies found that plasma BCAA levels can be associated with animal protein consumption. Dairy products and red meat contain the greatest amounts of BCAAs, although they are present in all protein-containing foods. Whey protein and egg protein supplements are other sources of BCAAs. Lowering the intake of these foods can lower the isoleucine plasma levels.
Possible treatment:
Lower your BCAA intake by focusing on a whole foods plant-based diet. Check also for sufficient vitamin B6 intake to aid metabolism.
Anthony
Unlimited Plan Member since 2021
I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
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Advanced Plan Member since 2020
What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!
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As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!
– Low BCAAs are an indication of chronic depletion from low protein intake, poor digestion, or increased utilization from chronic over-exercising.
– Studies have shown that low levels of isoleucine in plasma indicate an increased need for niacin. Chronic deficiency can cause hypoglycemia, loss of muscle mass, or inability to build muscle.
– Isoleucine and the other branched chain amino acids can be low as a result of zinc deficiency (zinc dependent intestinal peptidase), protein malnutrition or other gastrointestinal dysfunctions.
– A chronic deficiency of this AA can cause hypoglycemia and related problems and loss of muscle mass or inability to build muscle.
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Anthony
Unlimited Plan Member since 2021
I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
Karin
Advanced Plan Member since 2020
What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!
Paul
Healthmatters Pro Member since 2024
As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!
Healthmatters is a highly-personalized health dashboard.
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With a Healthmatters account, you can dive into the details of each biomarker and gain insights into the meaning behind your medical test data, anytime, anywhere.
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If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.
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For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you.
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Our goal has been to make your Healthmatters account as intuitive as possible.
We’ve crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.
1. Graph View:Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.
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Yes, you can download information from your account. We can compile your labs into a CSV file. To download all your labs, you can go to Account Settings, and at the bottom of the page, you will find a link to download your information.
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Yes, you can! We highly recommend activating Two-Factor Authentication (2FA) for your account. To do so, please navigate to the "Profile and Security" section of your account, where you will find instructions for activating 2FA.
Yes, you can. When entering values for the biomarker, you will see an "Edit Range" button. Click this button, and you'll have the option to enter a custom range.
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1-Methylhistidine, 1-Methylhistidine (Plasma), 2-,3-, and 4-Methylhippuric acid, 2-Methylhippuric Acid, 2-Methylsuccinic Acid, 3,4-Dihydroxyhydrocinnamic Acid, 3,5-Dihydroxybenzoic Acid, 3-Methylhistidine, 3-Methylhistidine (Plasma), 3-Phenylpropionylglycine, 4-Hydroxybenzoic Acid, 4-Hydroxyphenylacetic Acid, 4-Hydroxyphenylpyruvic Acid, 5-Hydroxyindoleacetic Acid, 8-Hydroxy-2'-deoxyguanosine, a-Hydroxybutyric Acid, a-Keto-b-methylvaleric Acid, a-Ketobutyric Acid, a-Ketoglutaric Acid, a-Ketoisocaproic Acid, a-Ketoisovaleric Acid, a-Aminoadipic Acid, a-Aminoadipic Acid (Plasma), Adipic Acid, Alanine, Alanine (Plasma), Aldosterone, Anserine, Anserine (Plasma), Anthranilic Acid, Arabinitol, Arginine, Arginine (Plasma), Arginosuccinic Acid, Arginosuccinic Acid (Plasma), Asparagine, Asparagine (Plasma), Aspartic Acid, Aspartic Acid (Plasma), b-Hydroxybutyric Acid, b-Hydroxyisovaleric Acid, b-Alanine, b-Alanine (Plasma), Benzoic Acid, Benzoylform, Branched Chain Alpha-Keto Organic Acids, Carnosine, Carnosine (Plasma), cis-Aconitic Acid, Citric Acid, Citrulline, Citrulline (Plasma), Cortisol, Cortisone, Creatinine, Cystathionine, Cystathionine (Plasma), Cystine, Cystine (Plasma), D-Lactic Acid, Equol, Ethanolamine, Ethanolamine (Plasma), Ethylmalonic Acid, Formiminoglutamic Acid, Fructose, Fumaric Acid, g-Aminobutyric Acid, g-Aminobutyric Acid (Plasma), Glucaric Acid, Glucose, Glutamic Acid, Glutamic Acid (Plasma), Glutamine, Glutamine (Plasma), Glutamine / Glutamate Ratio, Glutamine / Glutamate Ratio (Plasma), Glutaric Acid, Glycine, Glycine (Plasma), Glycylproline, Glycylproline (Plasma), GSG Index, Hexanoylglycine, Hippuric Acid, Histidine, Histidine (Plasma), Homocitrulline, Homocitrulline (Plasma), Homocystine, Homocystine (Plasma), Homogentisic Acid, Homovanillic Acid, Hydroxykynurenine, Hydroxyproline, Hydroxyproline (Plasma), Indoleacetic Acid, Isocitric Acid, Isoleucine/allo-Isoleucine, Isoleucine/allo-Isoleucine (Plasma), KT Ratio, KT Ratio (Plasma), Kynurenic Acid, Kynurenine, Kynurenine (Plasma), Lactic Acid, Leucine, Leucine (Plasma), Lysine, Lysine (Plasma), Malic Acid, Mandelic Acid, Methionine, Methionine (Plasma), Methylmalonic Acid, Microalbumin, Ornithine, Ornithine (Ornithine transcarbamylase), Ornithine (Plasma), Orotic Acid, Oxalic Acid, pH, Phenylacetic Acid, Phenylalanine, Phenylalanine (Plasma), Phosphate, Phosphoethanolamine, Phosphoethanolamine (Plasma), Picolinic Acid, Pimelic Acid, Proline, Proline (Plasma), Pyridoxic Acid, Pyroglutamic Acid, Pyruvic Acid, Quercetin, Quinolinic Acid, Sarcosine, Sarcosine (Plasma), Sebacic Acid, Serine, Serine (Plasma), Suberic Acid, Suberylglycine, Succinic Acid, Sulfocysteine, Sulfocysteine (Plasma), Tartaric Acid, Taurine, Taurine (Plasma), Threonine, Threonine (Plasma), Total Branched Chain Amino Acids, Total Branched Chain Amino Acids (Plasma), Tryptophan, Tryptophan (Plasma), Tyrosine, Tyrosine (Plasma), Valine, Valine (Plasma), Vannilylmandelic Acid, Xanthurenic Acid
