- BCAAs are key nitrogen donors in the form of glutamic acid, glutamine, and alanine.
- Elevated total BCAAs have been associated with obesity, weight loss, insulin resistance, and NAFLD.
- Elevated plasma BCAAs were associated with an increased risk of hypertension, cardiovascular disease.
- BCAAs are higher in a “Western” diet. Check B6 need.
- Lower levels seen in liver cirrhosis and urea cycle disorders.
- Decreased amino acids are seen with decreased protein and calorie intake; increased tissue uptake, and body losses (urine, sweat, etc.).
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