AKA: Glucarate / D-Glucaric Acid
- Urinary glucaric acid has been used as an indicator of induced hepatic drug metabolization and elevated with exposure to xenobiotics.
- Levels may indirectly represent P-450 activity or an end-product of the glucuronidation pathway.
- Calcium-D-glucarate is the calcium salt of D-Glucarate.
- Dietary glucaric acid and supplementation with calcium-D-glucarate may suppress cell proliferation and inflammation, induce apoptosis, and have anticancer properties. Glucaric acid from dietary plants may act as a nontoxic β-glucuronidase inhibitor. Glucaric acid is normally in equilibrium with D-glucaro-1,4- lactone, and an increase in dietary glucaric acid increased D-glucaro-1,4- lactone, which suppresses blood and tissue beta-glucuronidase activity. Vegetarians may have higher levels.
- It has been found increased with increased PCBs, toxins, and medications.
Glucarate helps your liver perform its important role in removing from your body many types of toxins such as pesticides, prescription drugs, food components, and intestinal bacteria.
Urinary glucaric acid has been used as an indicator of induced hepatic drug-metabolization and elevated with exposure to xenobiotics. Levels may indirectly represent P-450 activity or an end-product of the glucuronidation pathway. Calcium-D-glucarate is the calcium salt of D-Glucarate.
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It has been found increased with increased PCBs, toxins, and medications.
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