Pyridoxic Acid

Optimal Result: 0 - 98.3 nmol/mg Creatinine.

- Pyridoxic acid (4-Pyridoxate) is a catabolic product of vitamin B6 that is excreted in the urine. Pyridoxic acid represents > 90% of vitamin B6 species excreted in the urine, and 40-60% of dietary vitamin B6 intake. Urine 4-pyridoxic acid correlated with plasma PLP and RBC PLP.

- 4-Pyridoxic acid level varies according to vitamin B6 intake and responds within 1–2 weeks to vitamin B6 depletion and repletion. Very low levels (<dl on the report) may indicate B6 need, and very high levels may identify excess intake.

- Increased xanthurenic acid after a tryptophan load may occur in vitamin B6-deficient individuals.

- In a mathematical model without a tryptophan load, xanthurenic acid and kynurenine increased at a more pronounced deficiency. Kynurenic acid may be more sensitive but may also result in a slight decrease.

What does it mean if your Pyridoxic Acid result is too low?

Very low levels (<dl on the report) may indicate B6 need.

What does it mean if your Pyridoxic Acid result is too high?

Very high levels may identify excess intake of Vitamin B6.

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