8-hydroxy-2-deoxyguanosine measures the oxidative impact to DNA. 8-hydroxy-2-deoxyguanosine levels will be high if your total antioxidant protection is inadequate.
8-hydroxy-2-deoxyguanosine is a non-invasive marker of cell damage. Some cell damage is a normal part of metabolism, but it is kept to a minimum by the cell’s protective mechanisms. Under certain circumstances, the balance between the damaging chemicals and protective mechanisms can be upset, resulting in a condition termed “oxidative stress.” Although numerous cell damage products can be formed, the one most often studied is 8-OHdG. When oxidative damage occurs to the cells, repair mechanisms produce 8-OHdG, which is excreted unchanged in the urine. High levels reflect high oxidative stress to the cells.a
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Consider supplementing with Vitamin C, E, lipoic acid and NAC. Also consider using green tea, grapes and berries. Although an increase consumption of alcohol will have a detrimental impact on this marker, an occasional glass of red wine may be of value due to its high level of flavonoids.
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1-Methylhistidine, 2-Methylhippuric Acid, 2-Methylsuccinic Acid, 3,4-Dihydroxyhydrocinnamic Acid, 3,5-Dihydroxybenzoic Acid, 3-Methylhistidine, 3-Phenylpropionylglycine, 4-Hydroxybenzoic Acid, 4-Hydroxyphenylacetic Acid, 4-Hydroxyphenylpyruvic Acid, 5-Hydroxyindoleacetic Acid, 8-Hydroxy-2'-deoxyguanosine, a-Hydroxybutyric Acid, a-Ketobutyric Acid, a-Ketoglutaric Acid, a-Ketoisovaleric Acid, a-Aminoadipic Acid, a-Keto-b-methylvaleric Acid, a-Ketoisocaproic Acid, Adipic Acid, Alanine, Alanine (Plasma), Aldosterone, Anserine, Anthranilic Acid, Arabinitol, Arginine, Arginosuccinic Acid, Asparagine, Aspartic Acid, b-Hydroxybutyric Acid, b-Alanine, b-Hydroxyisovaleric Acid, Benzoic Acid, Benzoylform, Branched Chain Alpha-Keto Organic Acids, Carnosine, cis-Aconitic Acid, Citric Acid, Citrulline, Cortisol, Cortisone, Creatinine, Cystathionine (Plasma), Cystine, D-Lactic Acid, Equol, Ethanolamine, Ethylmalonic Acid, Formiminoglutamic Acid, Fructose, Fumaric Acid, g-Aminobutyric Acid, Glucaric Acid, Glucose, Glutamic Acid, Glutamine, Glutamine / Glutamate Ratio, Glutaric Acid, Glycine, Glycylproline, Hexanoylglycine, Hippuric Acid, Histidine, Homocitrulline, Homocystine (Plasma), Homogentisic Acid, Homovanillic Acid, Hydroxykynurenine, Hydroxyproline, Indoleacetic Acid, Isocitric Acid, Isoleucine/allo-Isoleucine (Plasma), KT Ratio (Plasma), Kynurenic Acid, Kynurenine (Plasma), Lactic Acid, Leucine (Plasma), Lysine, Malic Acid, Mandelic Acid, Methionine (Plasma), Methylmalonic Acid, Microalbumin, Ornithine, Orotic Acid, Oxalic Acid, Phenylacetic Acid, Phenylalanine (Plasma), Phosphate, Phosphoethanolamine, Picolinic Acid, Pimelic Acid, Proline, Pyridoxic Acid, Pyroglutamic Acid, Pyruvic Acid, Quercetin, Quinolinic Acid, Sarcosine, Sebacic Acid, Serine, Suberic Acid, Suberylglycine, Succinic Acid, Sulfocysteine, Tartaric Acid, Taurine, Threonine, Total Branched Chain Amino Acids (Plasma), Tryptophan (Plasma), Tyrosine (Plasma), Valine (Plasma), Vannilylmandelic Acid, Xanthurenic Acid