Isosatratoxin F is another trichothecene produced by Stachybotrys chartarum. Several animal studies have shown that isosatratoxin F can cause nasal and pulmonary toxicity when administered intranasally or intratracheally. They showed that pulmonary alveolus cells were injured following intratracheal instillation of isosatratoxin F with marked changes in surfactant synthesis and secretion.
References:
Etzel, R. A., Mycotoxins. JAMA 2002, 287 (4), 425-7. [L]
Isosatratoxin F
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