Satratoxin G is a macrocyclic trichothecene mycotoxin produced by commonly called black mold or Stachybotrys chartarum, that contribute to disorders associated with water-damaged buildings. They are potent inhibitors of protein translation that initiate both inflammatory gene expression and apoptosis in vitro after upstream activation of mitogen-activated protein kinases (MAPKs). These water-soluble mycotoxins could produce airborne particles which could facilitate entry and release into respiratory airway tissue that may selectively induce apoptosis in olfactory sensory neurons in the nose (rhinitis) and brain(mild focal encephalitis).
Satratoxin G
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