β-alanine is a breakdown product of carnosine and anserine, which are dipeptides from meat consumption. Although β-alanine’s properties are limited, its relationship to carnosine makes it important. Both have antioxidant properties. And carnosine is critical for pH buffering in skeletal muscle during exercise, but its formation can be limited by enzymatic factors. For this reason, supplementation with β-alanine is sometimes used to enhance carnitine and therefore improve athletic performance.
In addition to diet and supplementation, β-alanine can also be endogenously produced. This occurs via degradation of uracil in the liver but it can also be made by intestinal bacteria such as E. coli. Since β-alanine comes from meat consumption, endogenous production is the only source in vegetarian and vegan populations. Given their limited diets, vegetarians and vegans have lower levels of β-alanine and muscle carnosine compared to omnivores. There is also an interesting interplay between taurine and β-alanine. Taurine and β-alanine share the same skeletal muscle transporter, whereby β-alanine can inhibit taurine’s uptake into muscle. Elevated beta-alanine can sometimes deplete taurine leading to oxidative stress, causing tissue damage. Additionally, these two amino acids compete for the same reabsorption transporters in the kidney. Elevated β-alanine can contribute to renal wasting of taurine.
Levels may be elevated in meat consumption when dipeptides anserine and carnosine are elevated since they both contain β-alanine. Supplementation with β-alanine also results in elevated levels. Urinary beta-alanine excretion is associated with gut bacterial fermentation and elevated levels may indicate dysbiosis.
Elevated β-alanine can contribute to renal wasting of taurine give their unique relationship. The breakdown and metabolism of β-alanine requires vitamin B6-dependent enzymes. With that, a functional need for vitamin B6 can contribute to elevations. Lastly, there are very rare inborn errors of metabolism that can cause elevations of β-alanine.
Our specialized data entry service is designed to seamlessly integrate your laboratory results into your private dashboard. Just send in your lab test results—whether it's an image or a file—and our skilled data entry team will handle the rest. We accommodate various file formats like PDFs, JPGs, and Excel.
The first report is complimentary. After that, the data entry service is priced at $15 per report, unless it's part of your subscribed plan. It's an ideal solution whether you have numerous reports to upload or if your schedule doesn't permit self-data entry.
We strive to make the data entry process easy for you. Whether by offering dozens of templates to choose from that pre-populate the most popular laboratory panels or by giving you instant feedback on the entered values. Our data entry forms are an easy, fast, and convenient way to enter the reports yourself. There is no limit on how many lab reports you can upload.
track personal results
track multiple client's results
own it for life
for health professionals
for personal lab results
own it for life
Level up your lab report analysis with our Pro plan, built for health practitioners like you.
Health Business Account
Unlock additional Pro plans when you sign up.