DUTCH

Total Estrogen (male)

Optimal Result: 10 - 34 ng/mg.

What is Estrogen?

Estrogen is known as the “female” hormone. The four major naturally occurring estrogens in women are estrone (E1), estradiol (E2), estriol (E3), and estetrol (E4).

Although estrogen is identified with females, it is also found in men.

In women, estrogen helps initiate sexual development, regulates menstrual cycles, and affects the entire reproductive system.

Estrogen in men:

In men, estrogen also plays an important role in sexual function. As teenagers, men have high levels of testosterone and low levels of estrogen. As they age, testosterone levels in men decrease while their estrogen levels increase.

Estradiol (E2) in men is essential for modulating libido, erectile function, and spermatogenesis. Estrogen receptors and aromatase, the enzyme that converts testosterone to estrogen, are abundant in the brain, penis, and testis, organs important for sexual function. In the brain, estradiol (E2) synthesis is increased in areas related to sexual arousal. Also, in the penis, estrogen receptors are found. Low testosterone and elevated estrogen increase the incidence of erectile dysfunction independently of one another.

Resources:

  • The role of estradiol in male reproductive function [L]

What does it mean if your Total Estrogen (male) result is too high?

A healthy balance of estrogen and testosterone is important for sexual growth and development. When these hormones become imbalanced, sexual development and function may be affected.

Causes of Increased Levels of Estrogens in Men:

- Testosterone, DHEA, or pregnenolone supplementation

- Excessive aromatase activity (may be seen with obesity)

- Testicular, adrenal, or hepatic tumors

- Hepatic cirrhosis

- Adult-onset adrenal hyperplasia, Adrenal neoplasm

- Consider insulin resistance, as this is sometimes associated with overly active aromatization (testosterone -> E2) in men

Symptoms include:

  • Infertility. Estrogen is partly responsible for creating healthy sperm. When estrogen levels are high, sperm levels may fall and lead to fertility issues.
  • Gynecomastia. Estrogen may stimulate breast tissue growth. Men with too much estrogen may develop gynecomastia, a condition that leads to larger breasts.
  • Erectile dysfunction (ED). Men with high levels of estrogen may have difficulty getting or maintaining an erection.

Understand blood, stool, and urine medical results from your labs.

10 000+ happy clients
100% satisfaction
★★★★★ customer support

Essential Plan


  • Monthly subscription
  • Instant interpretation
  • Use the free self-upload form
  • Additional charge for upload service
  • 2000+ biomarkers explained
  • Recommendations
  • Cancel anytime

Advanced Plan


  • Yearly subscription
  • Instant interpretation
  • We upload five reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Online support
  • Cancel anytime

Own It For Life premium plan


  • No subscription
  • Unlimited access
  • Unlimited storage
  • Instant interpretations
  • We upload ten reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Dedicated support

Healthmatters.io software for professional use.

Welcome to Healthmatters Pro.

Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place.

Learn More


We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

General Data Protection Regulation (GDPR). HIPAA compliance for healthcare professionals
×

Understand Your Lab Result Now

  • Instant interpretation
  • 2000+ biomarkers explained
  • Science-based recommendations
  • Online support
  • Secure and private portal

Get 10% off with promocode:

;