VEGF stands for Vascular Endothelial Growth Factor. VEGF is a growth factor that promotes the growth of new blood vessels. The body makes VEGF in response to low oxygen levels, also known as hypoxia. Thus, when tissues are receiving too little oxygen rich blood flow, VEGF is produced to provide a better blood supply to the tissues. VEGF also increases the permeability or leakiness of blood vessels. In fact, one form of VEGF, VEGF-A was once known as vascular permeability factor. VEGF plays a role in cell metabolism, bone formation, and blood cell creation (hematopoiesis). Unfortunately, cancer cells also produce VEGF to help improve their own blood flow. Interestingly, cancer treatments have been developed to block the action of VEGF to starve cancerous tumors of blood flow.
Sources:
https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=vegf
https://www.uptodate.com/contents/overview-of-angiogenesis-inhibitors
http://www.questdiagnostics.com/testcenter/BUOrderInfo.action?tc=14512X&labCode=QER
The significance of a VEGF level that is too low is unknown.
Understand and improve your laboratory results with our health dashboard.
Upload your lab reports and get your interpretation today.
Our technology helps to understand, combine, track, organize, and act on your medical lab test results.
An elevated VEGF level in the serum may indicate the presence of cancer. Chronic states of hypoxia such as COPD may increase VEGF levels. In addition, people with serious or chronic wounds may have elevated VEGF levels. VEGF is produced in people with low platelet levels (thrombocytopenia).
Some specific causes of high VEGF are:
- Solid cancers (e.g. gastric cancer)
- Non-Hodgkin lymphomas,
- Acute myeloid and lymphoid leukemias,6,12,13
- Chronic myeloid and lymphoid leukemias13 and
- Myelodysplastic syndromes
- Idiopathic myelofibrosis
- Thrombocytopenia
Interpret Your Lab Results
Upload your lab report, and we'll interpret and provide you with recommendations today.
Get StartedOur specialized data entry service is designed to seamlessly integrate your laboratory results into your private dashboard. Just send in your lab test results—whether it's an image or a file—and our skilled data entry team will handle the rest. We accommodate various file formats like PDFs, JPGs, and Excel.
The first report is complimentary. After that, the data entry service is priced at $15 per report, unless it's part of your subscribed plan. It's an ideal solution whether you have numerous reports to upload or if your schedule doesn't permit self-data entry.
We strive to make the data entry process easy for you. Whether by offering dozens of templates to choose from that pre-populate the most popular laboratory panels or by giving you instant feedback on the entered values. Our data entry forms are an easy, fast, and convenient way to enter the reports yourself. There is no limit on how many lab reports you can upload.
Personal plans
track personal results
Professional Plan
track multiple client's results
$15/month
$250/once
own it for life
$45/month
for health professionals
Personal Account
$15/month
for personal lab results
$250/once
own it for life
Level up your lab report analysis with our Pro plan, built for health practitioners like you.
Health Business Account
$45/month
Unlock additional Pro plans when you sign up.
At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.
14.3.3 ETA PROTEIN, Acetylcholine Receptor (AChR) Antibody, Activated partial thromboplastin time (APTT), Alpha 2-Macroglobulins, Qn, Alpha Melanocyte Stimulating Hormone, ANA SCREEN A, ANA SCREEN B, ANA SCREEN, IFA, ANA Screen, IFA (Positive, Negative), ANA titer, Anti-C1Q Ab, IgG (RDL), Anti-DBL-Strand DNA Ab, Anti-dsDNA (Double-stranded) Ab by Farr method (RDL), Anti-dsDNA ab (Farr Assay), Anti-Smith Antibody, Anticardiolipin Ab, IgM, Anticardiolipin Ab,IgA,Qn, Anticardiolipin Ab,IgG,Qn, Antinuclear Antibodies (ANA) Screen, Reflex ANA IFA dsDNA Antibodies, Antinuclear Antibodies Direct (ANA Direct), Antiphosphatidylserine IgA, Antiphosphatidylserine IgG, Antiphosphatidylserine IgM, Baski sleepy, C1 Esterase Inhibitor, Func, C1 Esterase Inhibitor, Serum, C3A Desarg Fragment, C4a Level by RIA, CARDIOLIPIN AB (IGA), CARDIOLIPIN AB (IGG), CARDIOLIPIN AB (IGM), Carnitine Esters, Carnitine, Free, Carnitine, Total, CCP Antibodies IgG/IgA, Centromere, Chromatin, Coccidioides Ab by CF, Coccidioides Ab, IgG, EIA, Coccidioides Ab, IgM, EIA, Complement C3, Complement C3a, Complement C4, Serum, Complement C4a, Complement Component C1Q, Complement, Total (CH50), Complement, Total (CH50) / Quest, Cyclic Citrullinated Peptide Antibody, Dilute Russell's viper venom time (dRVVT), Diphtheria Antitoxoid Antibody, DNA AB Double Stranded Titer, DNA Double-Stranded Ab, IgG, DRVVT SCREEN, ds-DNA Antibody, IgG, dsDNA, ENA to Smith (Sm) Antibody, Eosinophil Cationic Protein (ECP), Erythrocyte Sedimentation Rate (ESR), Esterified/Free Ratio, F004-IgE Wheat, Free Kappa Lt Chains, Serum, Free Lambda Lt Chains, Serum, Gastrin, GlycA, Hemoglobin A2 (Quant), HISTAMINE RELEASE (CHRONIC URTICARIA), Histamine, Plasma, Histone, HLA-B27 (Human Leukocyte Antigen B27), Human Transforming Growth Factor Beta 1 (TGF-b1), IGE ANTIBODY (ANTI IGE IGG), Immature Grans (Abs), Immature Granulocytes (%), Immunofixation Result, Serum, Immunoglobulin A, Qn, Serum, Immunoglobulin D, Quant, Serum, IMMUNOGLOBULIN E, Immunoglobulin E, Total, Immunoglobulin G, Qn, Serum, Immunoglobulin M, Qn, Serum, Influenza Type A Antibody Serum, Influenza Type B Antibody Serum, Interleukin-2, Serum, Interleukin-6, Jo 1 Antibodies, IgG, Serum, JO-1, Kappa/Lambda Ratio, Serum, Liver Kidney Mic IgG, Liver-Kidney Microsomal Antibodies, Lupus Anticoagulant, Measles Antibodies, IgG, Mumps Abs, IgG, PEP A2Glob, PHOSPHATIDYLETHANOLAMINE AB (IGA), PHOSPHATIDYLETHANOLAMINE AB (IGG), PHOSPHATIDYLETHANOLAMINE AB (IGM), PHOSPHATIDYLSERINE AB (IGA), PHOSPHATIDYLSERINE AB (IGG), PHOSPHATIDYLSERINE AB (IGM), Plasminogen Activator Inhibitor (PAI-1) AG, Prothrombin Fragment 1.2, Prothrombin Time (PT), Prothrombin Time (PT) INR, RA Latex Turbid, Reptilase Clotting Time, RF, IgA by EIA (RDL), RF, IgG by EIA (RDL), RF, IgM by EIA (RDL), Rheumatoid factor (RF), RNA Polymerase III Antibodies, RNP/Sm, Scl-70, SICKLE CELL SCRN, Sirolimus, Whole Blood, Sm, SM/RNP Antibody, Smith/RNP (ENA) Ab, IGG, Smooth Muscle Abs, IFA, SSA, SSB, ssDNA, Tacrolimus, Whole Blood, Tetanus Antitoxoid IgG Ab, TGF-b1, Thrombin time, Thrombin-Antithrombin TAT, Trans. Growth Fact. beta 1, Transforming Growth Factor beta, Plasma, Tryptase, Tumor Necrosis Factor, Varicella-Zoster Virus (VZV) DNA, Qualitative, Real-Time PCR, VEGF, Plasma, Von Willebrand Factor Antigen (vWF), vWF Activity