Who should use Healthmatters?

Individuals who want to track and understand their health over time, health professionals, such as doctors, nutritionists, and wellness coaches, need to manage and interpret lab data for their clients.

What can I do with a Healthmatters account?

With a Healthmatters account, you can: Upload lab reports from any lab, View your data in interactive graphs, tables, and timelines, Track trends and monitor changes over time, Customize your reference ranges, Export and share your full lab history, Access your results anytime, from any device. Professionals can also analyze client data more efficiently and save time managing lab reports.

What test results do you interpret?

Healthmatters.io personal account provides in-depth research on 10000+ biomarkers, including information and suggestions for test panels such as, but not limited to: The GI Effects® Comprehensive Stool Profile, GI-MAP, The NutrEval FMV®, The ION Profile, Amino Acids Profile, Dried Urine Test for Comprehensive Hormones (DUTCH), Organic Acids Test, Organix Comprehensive Profile, Toxic Metals, Complete Blood Count (CBC), Metabolic panel, Thyroid panel, Lipid Panel, Urinalysis, And many, many more.

Do you only accept reports from specific labs listed here?

While we work with many popular labs, we welcome reports from lots of other places too. It's as simple as this: if you can get a test done, you can upload it to Healthmatters and we can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.

How do I get reports into my Healthmatters account?

There are two ways to add your test reports to your Healthmatters account. One option is to input the data using the data entry forms. The other method is to utilize our 'Data entry service.' Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values. For those who prefer assistance, we offer a 'Data entry service' to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you.

What is the Data Entry Service, and why does it cost $15 per report?

Our Data Entry Service is for when you don't want to manually type in your lab results yourself. You simply upload your report (PDF, image, or screenshot), and our trained team enters the information into your Healthmatters account for you — accurately and neatly organized, ready to view in graphs, tables, and timelines. The $15 per report covers the time and care it takes for a real person to review your file, make sure each result is entered correctly, and double-check for accuracy. This ensures your health data is precise and easy to work with — without you having to spend the time doing it yourself. Prefer to do it yourself? You can always use our free self-entry tool to add results manually — it just takes a bit more time and attention.

Does a personal account come with a data entry service?

For users on the Advanced Plan, the first 5 reports are included free of charge, and each additional report incurs a $15 fee. Unlimited Plan holders enjoy the entry of 10 reports at no charge. Subsequent reports are subject to a $15 fee per report. Additionally, users on the Advanced Plan can upgrade to the Unlimited Plan from their account settings.

How much does a professional account cost?

All professional accounts allow you to import and onboard an unlimited number of clients and their lab results. The distinction between professional plans lies solely in the data entry service. The Pro Monthly Plus plan is priced at $75 per month and includes a data entry service for five reports each month. Additional reports can be self-entered at no extra cost or, if preferred, you can use our data entry service for an additional fee of $15 per report. The Pro Monthly plan is priced at $45 per month and does not include a data entry service. Self-entry is free for an unlimited number of reports, and you can opt for the data entry service at a fee of $15 per report. You also have the option to upgrade to higher monthly or to annual plans, which come with substantial discounts. All upgrades can be done directly from your account.

How do I terminate my account?

Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.

Can I download my information from my account?

Yes, you can download your information anytime. We offer two easy ways to export your lab data: 1. Download a CSV file: Go to Account Settings and scroll to the bottom of the page. There, you'll find a link to download all your labs as a CSV file. 2. Download an Excel file: To export your data in Excel format, go to either the Graph or Table view and click “Export Excel File.”

Can I print my report?

Yes, you can print your report. To do so, navigate to 'All tests' and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.

Can I secure my account with Two-Factor Authentication (2FA)?

Yes, you can! We highly recommend activating Two-Factor Authentication (2FA) for your account. To do so, please navigate to the 'Profile and Security' section of your account, where you will find instructions for activating 2FA.

Can I use a custom range for biomarkers?

Yes, you can. When entering values for the biomarker, you will see an 'Edit Range' button. Click this button, and you'll have the option to enter a custom range.

What’s the difference between personal and professional accounts?

A personal account is all about keeping your own lab test results in check. It's just for you and your personal use. The professional account is designed for health professionals who wish to track and organize their clients' laboratory results.

Where can I learn more about professional accounts?

To learn more about Healthmatters Pro, please refer to the professional page.

Can I share my results in the HealthMatters dashboard with my doctor?

Yes, you can! Simply go to the 'Invite Doctor' section, enter your doctor’s email address, and send the invitation. Your doctor will receive an email with secure access to view your results. You can revoke this access at any time. All shared information is securely encrypted and protected for your privacy.

Can I export my information to an Excel file?

Yes, you can! Go to the Graph view or Spreadsheet view. In the top-right corner, click 'Export to Excel,' and the file will be downloaded to your device.

C1 Esterase Inh. Ag (Antigen)

Other names: C1 Esterase Inh. Ag

Optimal Result: 19 - 37 mg/dL.

Immune System

C1 Esterase Inh. Ag (Antigen) – What Your Lab Test Means

What is C1 Esterase Inhibitor Antigen (C1-INH Ag)?

C1 Esterase Inhibitor Antigen, often abbreviated as C1-INH Ag, is a blood test that measures the amount of C1 esterase inhibitor protein in your blood. This protein plays a crucial role in regulating parts of your immune system and the complement system, which helps fight infections and control inflammation.

Why is this marker important?

C1 esterase inhibitor helps keep your immune system in balance by preventing excessive activation of the complement pathway, a part of your immune defense. If you don’t have enough of this protein, or if it’s not working properly, it can lead to uncontrolled inflammation and swelling in the body.

What does this test diagnose?

This test is most commonly used to help diagnose Hereditary Angioedema (HAE) Type I — a rare but serious genetic condition that causes sudden, recurrent episodes of swelling in the face, throat, abdomen, limbs, or airway.

It may also be used to evaluate:

Acquired angioedema (AAE), which can occur in adults due to other conditions like lymphomas or autoimmune disorders.
Unexplained recurrent swelling or abdominal pain without allergic triggers.

What do the results mean?

C1-INH Antigen Level	Possible Interpretation
Low	Suggests Type I Hereditary Angioedema (HAE) or Acquired Angioedema (AAE)
Normal or High	If symptoms persist, a functional C1-INH test may be needed to check whether the protein is working properly (to rule out Type II HAE)

It’s important to interpret this result alongside C4 levels and possibly a C1-INH functional assay for a full diagnostic picture.

Symptoms that may prompt this test

Swelling of the face, lips, tongue, throat, or extremities
Abdominal pain, cramping, or bloating
Difficulty breathing during swelling episodes
No response to standard allergy medications (like antihistamines or steroids)

How is the test performed?

A blood sample is drawn, usually from a vein in your arm. No special preparation is needed in most cases.

Related Tests

Doctors often order additional tests alongside C1-INH Ag for a more complete diagnosis:

C1 Esterase Inhibitor, Functional – Measures whether the protein works properly
Complement C4 levels – Often low during HAE attacks
C1q level – May help differentiate hereditary vs. acquired angioedema

Bottom Line

The C1 Esterase Inh. Ag (Antigen) test measures how much of this critical immune-regulating protein is in your blood. A low result can point to Type I Hereditary Angioedema, a condition that causes episodes of swelling that can be life-threatening if untreated. If your antigen level is normal but symptoms continue, your doctor may order further tests to check how well the protein is functioning.

What does it mean if your C1 Esterase Inh. Ag (Antigen) result is too high?

What Do Elevated Levels of C1 Esterase Inhibitor Antigen (C1-INH Ag) Indicate?

Elevated levels of C1 esterase inhibitor antigen (C1-INH Ag) are uncommon and, by themselves, are usually not clinically significant. This test is most often used to detect low levels of the protein in conditions such as Hereditary Angioedema (HAE) Type I or Acquired Angioedema (AAE). However, if your C1-INH Ag levels are above the reference range, here’s what it may mean:

1. Acute-Phase Reaction or Inflammation

C1-INH is a serine protease inhibitor and can act as an acute-phase protein. Its levels may rise modestly in response to:

Inflammation
Infection
Tissue injury
Autoimmune activity

However, this increase is generally less pronounced and less consistent than with other acute-phase proteins like C-reactive protein (CRP) or serum amyloid A (SAA). In these cases, elevated C1-INH Ag reflects a nonspecific immune response.

2. Compensatory Response or Protein Dysfunction

Rarely, elevated C1-INH Ag may reflect a compensatory increase in production due to chronic activation of the complement or contact systems. In Hereditary Angioedema Type II (HAE-II), for example:

C1-INH Ag levels may be normal or even elevated (sometimes significantly above the reference range)
The protein is dysfunctional and does not work properly

This paradoxical elevation can serve as a clue for HAE-II, especially when accompanied by low C4 levels.

3. Normal Genetic Variation

Some individuals may naturally have higher C1-INH Ag levels due to genetic variation or minor laboratory fluctuation, without any clinical consequence.

4. Laboratory Interference or Error

As with any laboratory test, spurious elevation can occur due to:

Sample handling or processing issues
Concurrent medications
Technical variability in assay methods

Important Note: Function Over Quantity

An elevated C1-INH antigen level does not guarantee that the protein is functioning correctly. For example, in HAE-II:

C1-INH Ag may be normal or high
The protein is dysfunctional

Functional testing is essential to determine whether the C1-INH protein is working as it should.

Diagnostic Clues and Next Steps

If your C1-INH Ag is elevated, your clinician may consider:

Ordering a C1-INH functional assay to assess protein activity
Testing C4 and C1q levels to evaluate complement system activity
- Low C4 with normal C1q: Suggests HAE-II
- Low C4 with low C1q: Suggests AAE
Reviewing symptoms, medical history, and other inflammatory markers

Summary

Elevated C1 esterase inhibitor antigen levels are usually not a cause for concern on their own and are most often seen in the context of inflammation, protein dysfunction (as in HAE-II), or laboratory variation. They are not associated with angioedema unless accompanied by symptoms and other abnormal complement markers. If elevated C1-INH Ag is found, further functional and complement testing is recommended to guide diagnosis and management.

All Your Lab Results.
One Simple Dashboard.

Import, Track, and Share Your Lab Results Easily

Import, Track, and Share Your Lab Results

Import lab results from multiple providers, track changes over time, customize your reference ranges, and get clear explanations for each result. Everything is stored securely, exportable in one organized file, and shareable with your doctor—or anyone you choose.

Cancel or upgrade anytime

Laboratories

Bring All Your Lab Results Together — In One Place

We accept reports from any lab, so you can easily collect and organize all your health information in one secure spot.

Pricing Table

Gather Your Lab History — and Finally Make Sense of It

Finally, Your Lab Results Organized and Clear

Choose the plan that fits you — and turn scattered lab reports into clear insights you can finally use.

Pick a plan that fits you — and turn scattered lab reports into clarity.

Personal plans

Professional plan

$79/ year

Advanced Plan

Access your lab reports, explanations, and tracking tools.

Import lab results from any provider
Track all results with visual tools
Customize your reference ranges
Export your full lab history anytime
Share results securely with anyone
Receive 5 reports entered for you
Cancel or upgrade anytime

$250/ once

Unlimited Account

Pay once, access everything—no monthly fees, no limits.

Import lab results from any provider
Track all results with visual tools
Customize your reference ranges
Export your full lab history anytime
Share results securely with anyone
Receive 10 reports entered for you
No subscriptions. No extra fees.

Professional plan

$45/ month

Pro Monthly

Designed for professionals managing their clients' lab reports

Import lab results from any provider
Track lab results for multiple clients
Customize reference ranges per client
Export lab histories and reports
Share results and reports with clients
Invite clients to their accounts
Begin with first report entered by us
Cancel or upgrade anytime

About membership

What's included in a Healthmatters membership

Import Lab Results from Any Source

Easily upload lab results from any provider, whether it's a hospital, independent lab, or home testing service. We support PDFs, scanned documents, and JPEGs from patient portals. No need to log in to multiple platforms — everything is centralized in one secure space.

Easily upload lab results from any provider — we support PDFs, scans, and images. Keep all your reports organized in one secure place.

See Your Health Timeline

Every lab result is automatically organized on a chronological timeline, giving you a complete picture of your health journey. Whether you're tracking a condition, managing treatments, or staying proactive, the timeline helps you and your doctor understand how things progress over time.

Every lab result is automatically organized on a chronological timeline, giving you a complete picture of your health journey.

Understand What Your Results Mean

Whether it's a blood test, GI panel, urinalysis, or something else, lab reports measure numerous biomarkers that reveal what's happening inside your body. Our extensive database covers over 10,000 biomarkers, providing clear, simple explanations of what each result means and how you can take action—no matter your membership level. Say goodbye to confusion and get the insights you need to better understand your health.

Our database covers over 10,000 biomarkers with clear, simple explanations—so you can finally understand your results and what to do next.

Enter Your Lab Reports Yourself — Always Free Enter Your Lab Reports — Always Free

If you'd like to handle inputting your health data into your account, you can do so with our easy-to-use data entry forms. Our user-friendly form is designed to guide you through the quick and easy submission process, making it simple to keep track of your health metrics. This is available to both Advanced plan and Unlimited plan members.

Our user-friendly form guides you through a quick, simple submission process, making it easy to enter your health metrics.

Add your results anytime with our easy entry form. It's quick, guided, and helps you stay organized — free for all members.

Visualize Your Results

View your lab data through easy-to-read graphs and tables. Quickly spot patterns, track changes, and compare results across different dates — all without digging through multiple reports. You can also select and compare graphs of specific biomarkers side-by-side to better understand how they relate and change over time.

See your lab reports in clear graphs and tables. Spot patterns, track changes, and compare results over time — all in one place.

Export Your Complete Lab History in a Single File Export Your Complete Lab History

After collecting lab results from different providers, you can download your entire history combined into a single file. Choose from PDF, Excel, or CSV formats to easily review, share, or get a second opinion—no more juggling multiple reports.

After collecting lab results from different providers, you can download your entire history combined into a single file.

Comprehensive Data Entry Service for Your Reports Data Entry Service for Your Reports

Our inclusive service handles the data entry for your lab reports. Just submit your information and we'll take care of the rest. Advanced plan members receive five reports entered for free, then $15 per report after that. Unlimited plan members receive ten report entries for free, then $15 per report after that.

Our inclusive service handles the data entry for your lab reports. Just submit your information and we'll take care of the rest.

Securely Share With Anyone You Trust

Whether you're working with a doctor, nutritionist, caregiver, or wellness coach, you can securely share your complete lab history by sending an invite link to anyone you trust. You have full control over who sees your information and for how long, ensuring your privacy and peace of mind at every step.

Share your full lab history with your doctor, nutritionist, or coach using a secure invite link.

Discover

Let Your Lab Results Tell the Full Story

Once your results are in one place, see the bigger picture — track trends over time, compare data side by side, export your full history, and share securely with anyone you trust.

Bring all your results together to compare, track progress, export your history, and share securely.

I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.

Anthony

Unlimited Plan Member since 2021

What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!

Karin

Advanced Plan Member since 2020

As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!

Paul

Healthmatters Pro Member since 2024

Frequently asked questions

Healthmatters is a personal health dashboard that helps you organize and understand your lab results. It collects and displays your medical test data from any lab in one secure, easy-to-use platform.

Individuals who want to track and understand their health over time.
Health professionals, such as doctors, nutritionists, and wellness coaches, need to manage and interpret lab data for their clients.

With a Healthmatters account, you can:

Upload lab reports from any lab
View your data in interactive graphs, tables, and timelines
Track trends and monitor changes over time
Customize your reference ranges
Export and share your full lab history
Access your results anytime, from any device

Professionals can also analyze client data more efficiently and save time managing lab reports.

Healthmatters.io personal account provides in-depth research on 10000+ biomarkers, including information and suggestions for test panels such as, but not limited to:

The GI Effects® Comprehensive Stool Profile,
GI-MAP,
The NutrEval FMV®,
The ION Profile,
Amino Acids Profile,
Dried Urine Test for Comprehensive Hormones (DUTCH),
Organic Acids Test,
Organix Comprehensive Profile,
Toxic Metals,
Complete Blood Count (CBC),
Metabolic panel,
Thyroid panel,
Lipid Panel,
Urinalysis,
And many, many more.

You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.

If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.

The Advanced Plan ($79/year) is perfect for individuals who want ongoing access to their health data. It includes unlimited self-entry of lab reports, visual tracking, custom ranges, result explanations, full account exports, and secure sharing — all with a simple yearly subscription. The plan also includes free data entry of up to 5 reports by our data entry team. You can cancel anytime and restart your plan whenever you're ready — your data will still be there waiting for you. You can also upgrade to the Unlimited Plan at any time, with the cost prorated based on what you've already paid.

The Unlimited Plan ($250 one-time) is also designed for individuals but offers lifetime access with no ongoing subscription. You'll get all the same features as the Advanced Plan, plus free data entry of up to 10 reports by our data entry team, making it a great choice if you prefer a one-time payment and long-term use without yearly fees.

In short:

Advanced Plan → Best for those who want to try the service for less (cancel/restart anytime, upgrade to Unlimited anytime).
Unlimited Plan → Best for long-term users who prefer to pay once and keep access forever.

Our goal has been to make your Healthmatters account as intuitive as possible.

We've crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.

1. Graph View:

Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.

2. All Tests View

Explore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.

3. Table View:

For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.

We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.