ANA IFA is a first line screen for detecting the presence of up to approximately 150 autoantibodies in various autoimmune diseases. A positive ANA IFA result is suggestive of autoimmune disease and reflexes to titer and pattern. Further laboratory testing may be considered if clinically indicated.
A negative ANA IFA result suggests that ANA-associated autoimmune diseases are not present, but does not rule out the possibility. Patients with negative results on the ANA IFA usually also have negative results for specific ANA antibodies. However, Jo-1 antibody may be detected in ANA IFA-negative patients with some types of myositis, and SSA antibody may be present in some ANA IFA-negative patients with SLE or Sjögren's syndrome.
ANA IFA is a first line screen for detecting the presence of up to approximately 150 autoantibodies in various autoimmune diseases. A positive ANA IFA result is suggestive of autoimmune disease and reflexes to titer and pattern. Further laboratory testing may be considered if clinically indicated.
A positive result on the ANA IFA screen suggests the presence of autoimmune disease, and will reflex to titer and pattern. A low ANA titer (1:40 to 1:80) may be associated with preclinical disease or lack of disease. Titers >1:80 are consistent with autoimmune disease. In cases of positive ANA, the staining pattern helps predict the disease type.
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Acetylcholine Receptor Ganglionic (Alpha 3) AB, Actin (Smooth muscle) Antibody (IgG), ANA SCREEN, IFA, ANA titer, B2 GLYCOPROTEIN I (IGA)AB, B2 GLYCOPROTEIN I (IGG)AB, B2 GLYCOPROTEIN I (IGM)AB, CARDIOLIPIN AB (IGA), CARDIOLIPIN AB (IGG), CARDIOLIPIN AB (IGM), CARNITINE ESTERS, CARNITINE, FREE, CARNITINE, TOTAL, CHROMOGRANIN A, COPEPTIN, Cortisol, Free, Urine, CORTISOL,FREE,LC/MS,S, DRVVT SCREEN, ESTERIFIED/FREE RATIO:, ESTRADIOL (Quest), GLUCOSE-6-PHOSPHATE DEHYDROGENASE, Hepatitis B Surface Antibody, Qualitative, HISTAMINE RELEASE (CHRONIC URTICARIA), HISTAMINE, PLASMA, IGF 1, LC/MS, IMMUNOGLOBULIN M, Immunoglobulin Subclass 4, INTRINSIC FACTOR BLOCKING ANTIBODY, IODINE, RANDOM URINE, LH, LKM-1 Antibody (IgG), LUPUS ANTICOAGULANT, Neuron Specific Enolase (NSE), PARATHYROID HORMONE, INTACT, PARTIAL THROMBOPLASTIN TIME, ACTIVATED, PHOSPHATIDYLETHANOLAMINE AB (IGA), PHOSPHATIDYLETHANOLAMINE AB (IGG), PHOSPHATIDYLETHANOLAMINE AB (IGM), PHOSPHATIDYLSERINE AB (IGA), PHOSPHATIDYLSERINE AB (IGG), PHOSPHATIDYLSERINE AB (IGM), PREGNENOLONE, LC/MS, PROGESTERONE, LC/MS, PROLACTIN-2, PROSTAGLANDIN D2 (PG D2), URINE, PROSTAGLANDINS (PG D2), SERUM/PLASMA, PROSTAGLANDINS: (PLASMA/SERUM), PROTHROMBIN ANTIBODY (IGG), PTT-LA SCREEN, Soluble Liver Antigen (SLA) Autoantibody, T3 REVERSE, LC/MS/MS, T3, FREE, TESTOSTERONE,BIOAVAILABLE, TRYPTASE, TSI - Thyroid-Stimulating Immunoglobulin, Serum, Z SCORE (FEMALE)
