A healthy result should fall into the range 26 - 36 seconds.
The Activated partial thromboplastin time (aPTT) test tells you how many seconds (s) it takes your blood to form a clot after body tissue(s) or blood vessel walls were injured. Normally, when one of your blood vessels is damaged, proteins in your blood called clotting factors come together in a certain order to form blood clots and quickly stop bleeding. The aPTT test can be used to look at how well those clotting factors are working. It’s often used with other tests that monitor clotting factors.
Difference between the PTT and aPTT tests:
They both measure the same thing, however, in aPTT, an activator is added that speeds up the clotting time and results in a narrower reference range. The aPTT is considered a more sensitive version of the PTT and is used to monitor the patient’s response to heparin therapy.
Some reason to take this test:
Symptoms of bleeding disorders:
Test results are measured in seconds of time. Your results will show how long your blood took to clot, and will often compare them with results from a normal sample tested at the same time. What’s normal varies with different labs, so check with your doctor to help you understand what your numbers mean.
The APTT is frequently performed as part of a series of screening tests that comprise the PT, APTT and often the thrombin time and an estimation of the fibrinogen concentration.
It’s important to rule out interfering factors of an abnormal aPTT before undertaking a more detailed investigation:
Shortening of the aPTT usually reflects either elevation of factor VIII activity in vivo that most often occurs in association with acute or chronic illness or inflammation, or spurious results associated with either difficult venipuncture and specimen collection or suboptimal specimen processing.
Prolongation of the activated partial thromboplastin time (aPTT) can occur as a result of:
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