Activated partial thromboplastin time (APTT)

Other names: Activated Partial Thrombopl Time, P

check icon Optimal Result: 22.9 - 30.2 seconds.

The Activated partial thromboplastin time (aPTT) test tells you how many seconds (s) it takes your blood to form a clot after body tissue(s) or blood vessel walls were injured. Normally, when one of your blood vessels is damaged, proteins in your blood called clotting factors come together in a certain order to form blood clots and quickly stop bleeding. The aPTT test can be used to look at how well those clotting factors are working. It’s often used with other tests that monitor clotting factors.

Difference between the PTT and aPTT tests:

They both measure the same thing, however, in aPTT, an activator is added that speeds up the clotting time and results in a narrower reference range. The aPTT is considered a more sensitive version of the PTT and is used to monitor the patient’s response to heparin therapy.

Some reason to take this test:

- To check for a bleeding disorder like hemophilia or von Willebrand disease.

- If you get heparin therapy.

- Check that your blood clots normally before you go in for surgery

- Look for a problem with your immune system (some immune system conditions make clots more likely to form — in women, that can also lead to miscarriages)

- See how well your liver’s working, since it makes the clotting factors

Symptoms of bleeding disorders:

- Bleeding or bruising easily

- Blood clots that form when they shouldn’t

- Blood in your poop or urine

- Gums that bleed easily

- Heavy menstrual periods in women

- Nosebleeds

- Swelling or pain in your joints

Normal Ranges:

Test results are measured in seconds of time. Your results will show how long your blood took to clot, and will often compare them with results from a normal sample tested at the same time. What’s normal varies with different labs, so check with your doctor to help you understand what your numbers mean.

- A typical aPTT value is 30 to 40 seconds. If you get the test because you’re taking heparin, you’d want your aPTT results to be more like 60 to 80 seconds.

The APTT is frequently performed as part of a series of screening tests that comprise the PT, APTT and often the thrombin time and an estimation of the fibrinogen concentration.

Interfering factors:

It’s important to rule out interfering factors of an abnormal aPTT before undertaking a more detailed investigation:

- unfractionated heparin in a central venous or arterial catheter can prolong aPTT.

- A high hematocrit value will give falsely prolonged aPTT. This is due to the increased concentration of citrate relative to the small volume of plasma.

References:

- Clinical and Laboratory Standards Institute (CLSI). One-stage PT and APTT test; Approved Guideline Second Edition. H47-A2, 2008

- Greaves M, Preston FE: Approach to the bleeding patient. In Hemostasis and Thrombosis: Basic Principles and Clinical Practice. Fourth edition. Edited by RW Colman, J Hirsh, VJ Marder, et al. Philadelphia, JB Lippincott Co, 2001, pp 1197-1234

What does it mean if your Activated partial thromboplastin time (APTT) result is too high?

Prolongation of the activated partial thromboplastin time (aPTT) can occur as a result of:

- deficiency of one or more coagulation factors (acquired or congenital in origin), or

- the presence of an inhibitor of coagulation such as heparin,

- a lupus anticoagulant,

- a nonspecific inhibitor such as a monoclonal immunoglobulin, or

- a specific coagulation factor inhibitor.

- Prolonged clotting times may also be observed in cases of fibrinogen deficiency, liver disease, and vitamin K deficiency.

All Your Lab Results.
One Simple Dashboard.

What does it mean if your Activated partial thromboplastin time (APTT) result is too low?

Shortening of the aPTT usually reflects either elevation of factor VIII activity in vivo that most often occurs in association with acute or chronic illness or inflammation, or spurious results associated with either difficult venipuncture and specimen collection or suboptimal specimen processing.

Laboratories

Bring All Your Lab Results Together — In One Place

We accept reports from any lab, so you can easily collect and organize all your health information in one secure spot.

lab corp logo
genova diagnostics logo
quest diagnostics logo
dutch test logo
doctors data logo
vibrant america logo
diagnostic solutions logo
zrt laboratory logo
the great plains laboratory logo
cyrex laboratories logo
spectracell logo

Pricing Table

decoration

Personal plans

$15/ month

Complete Plan

Access your lab reports, explanations, and tracking tools.

  • Import lab results from any provider
  • Track all results with visual tools
  • Customize your reference ranges
  • Export your full lab history anytime
  • Share results securely with anyone
  • Begin with first report entered
  • Cancel or upgrade anytime

$250/ once

Unlimited Account

Pay once, access everything—no monthly fees, no limits.

  • Import lab results from any provider
  • Track all results with visual tools
  • Customize your reference ranges
  • Export your full lab history anytime
  • Share results securely with anyone
  • Receive 10 reports entered for you
  • Skip the $15/month subscription — no recurring payments ever

$45/ month

Pro Monthly

Designed for professionals managing their clients' lab reports

  • Import lab results from any provider
  • Track lab results for multiple clients
  • Customize reference ranges per client
  • Export lab histories and reports
  • Begin with first report entered by us
  • Cancel or upgrade anytime

About membership

What's included in a Healthmatters membership

microscope icon Import Lab Results from Any Source

person icon See Your Health Timeline

book icon Understand What Your Results Mean

textbook icon

textbook icon Visualize Your Results

folder icon

folder icon

card icon Securely Share With Anyone You Trust

Let Your Lab Results Tell the Full Story

What Healthmatters Members Are Saying

5 stars rating

I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with  any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.

Anthony

Unlimited Plan Member since 2021

5 stars rating

What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!

Karin

Advanced Plan Member since 2020

5 stars rating

As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!

Paul

Healthmatters Pro Member since 2024

Use promo code to save 10% off any plan.

Frequently asked questions

Healthmatters is a personal health dashboard that helps you organize and understand your lab results. It collects and displays your medical test data from any lab in one secure, easy-to-use platform.

  • Individuals who want to track and understand their health over time.
  • Health professionals, such as doctors, nutritionists, and wellness coaches, need to manage and interpret lab data for their clients.

With a Healthmatters account, you can:

  • Upload lab reports from any lab
  • View your data in interactive graphs, tables, and timelines
  • Track trends and monitor changes over time
  • Customize your reference ranges
  • Export and share your full lab history
  • Access your results anytime, from any device

Professionals can also analyze client data more efficiently and save time managing lab reports.

Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:

  • The GI Effects® Comprehensive Stool Profile,
  • GI-MAP,
  • The NutrEval FMV®,
  • The ION Profile,
  • Amino Acids Profile,
  • Dried Urine Test for Comprehensive Hormones (DUTCH),
  • Organic Acids Test,
  • Organix Comprehensive Profile,
  • Toxic Metals,
  • Complete Blood Count (CBC),
  • Metabolic panel,
  • Thyroid panel,
  • Lipid Panel,
  • Urinalysis,
  • And many, many more.

You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.

If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.

shield icon

We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

gdpr compliance image hipaa compliance image