The SSA-60 (Ro60) Antibody, IgG biomarker is a specific autoantibody often tested as part of an ENA (Extractable Nuclear Antigen) panel to aid in diagnosing autoimmune conditions. Elevated levels of SSA-60 (Ro60) antibodies are commonly associated with Sjögren’s syndrome and systemic lupus erythematosus (SLE), indicating the immune system's abnormal targeting of Ro60 proteins, a component of RNA-protein complexes. This marker is particularly valuable in detecting autoimmune activity, even in cases where other tests may be inconclusive. Healthcare providers may order this test when symptoms like dry eyes, dry mouth, fatigue, or joint pain suggest autoimmune disease. Accurate interpretation of SSA-60 (Ro60) antibody levels, combined with clinical history and other diagnostic tests, can help confirm a diagnosis and guide personalized treatment strategies. Regular monitoring is also essential for tracking disease progression or response to therapy.
Every lab result you’ve ever had, charted and explained.
Healthmatters is a tracker for your lab results. Upload a report from any lab, any country — every marker charted and explained.
Start with my report →All our content is backed by peer-reviewed studies, academic research, and trusted medical sources. We’re committed to accuracy and transparency — see our editorial policy for details.