Brain Health

Biomarkers included in this panel:

ABETA 42/40 RATIO

The Aβ42/40 Ratio (Amyloid Beta 42/40 Ratio) is a biomarker that helps detect early signs of Alzheimer’s disease by measuring the balance between two key amyloid beta proteins in the blood or cerebrospinal fluid. A lower ratio indicates a

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Beta-amyloid 42/40 Ratio

The Beta-amyloid 42/40 ratio (Aβ42/40) compares two amyloid-beta peptides in blood or CSF to detect Alzheimer’s-type biology: because Aβ42 more readily forms plaques, its level in fluids falls relative to Aβ40, so a lower ratio i

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Neurofilament Light Chain (NfL)

Serum

Neurofilament proteins are vital structural components of nerve cells, helping to maintain their shape and function. Of these, neurofilament light chain (NfL) has emerged as a clinically important biomarker. When neurons are damaged or unde

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p-tau181

p-tau181 (phosphorylated tau at threonine 181) is a biomarker that reflects Alzheimer’s-type brain changes involving amyloid plaques and tau buildup. Measured in cerebrospinal fluid (CSF) or blood, it helps distinguish Alzheimer’s disease

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p-tau217

p-tau217 is a phosphorylated form of tau (at threonine 217) measured in blood or CSF that reflects Alzheimer’s-type biology—particularly amyloid plaque and tau changes—and often outperforms older phospho-tau markers like p-tau181 fo

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Quest AD-Detect® Phosphorylated tau217 (p-tau217), Plasma

Plasma

This test measures levels of phosphorylated tau217 (p-tau217) in the blood—a protein strongly linked to the development of Alzheimer’s disease and other neurodegenerative conditions. Tau proteins normally help stabilize nerve cells in the

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