Coxsackie A16 IgG
Serum
belonging to the Picornavirus family
Coxsackie A IgG Antibody
The Coxsackie Antibody, IgG test is used to detect antibodies against the Coxsackie virus in the blood. This condition is most common in children under the age of five, and it can cause Hand, Foot, and Mouth disease.
Coxsackieviruses are part of the enterovirus family of viruses (which also includes polioviruses and hepatitis A virus) that can live in the human digestive tract. In most cases, coxsackievirus infections cause mild flu-like symptoms and go away without treatment. But in some cases, they can lead to more serious infections. The viruses can spread from person to person, usually on unwashed hands and surfaces contaminated by feces, where they can live for several days.
Biomarkers in this category
4 biomarkers · optimal ranges shown
Coxsackie A24 IgG
Serum
belonging to the Picornavirus family
Coxsackie A7 IgG
Serum
Coxsackievirus A7 (CVA7) is a rarely detected and poorly characterized virus that belongs to the Enterovirus A species and has three strains: Parker, USSR, and 275/58. Despite a difference in pathogenicity among the three strains, they can all be typed by CVA7-specific neutralizing antibodies. CVA7 is most closely related to CVA14, CVA16, and Enterovirus 71 (EV71), and is associated with hand, foot and mouth disease (HFMD). CVA7 is neurotropic and can cause paralytic poliomyelitis. CVA7 was widely detected in the 1950s and 1960s during paralytic epidemics. A positive test result does not necessarily indicate current or recent infection as antibodies to Coxsackie species can be detected in uninfected individuals due to moderate passive exposure to infected hosts. It is, therefore, crucial that results from all Coxsackie A serologies correlate with the clinical history of the patient and all other data available to the physician. Samples collected at the early stage of infection (primarily in children) may not yield detectable antibodies. If a recent infection is suspected, a second specimen should be collected 10 to 20 days following the initial collection and tested. References: Yamayoshi S, Iizuka S, Yamashita T, Minagawa H, Mizuta K, Okamoto M, Nishimura H, Sanjoh K, Katsushima N, Itagaki T, Nagai Y, Fujii K, Koike S. Human SCARB2-dependent infection by coxsackievirus A7, A14, and A16 and enterovirus 71. J Virol. 2012 May;86(10):5686-96. doi: 10.1128/JVI.00020-12. Epub 2012 Mar 21. PMID: 22438546; PMCID: PMC3347270. Seitsonen JJ, Shakeel S, Susi P, Pandurangan AP, Sinkovits RS, Hyvönen H, Laurinmäki P, Ylä-Pelto J, Topf M, Hyypiä T, Butcher SJ. Structural analysis of coxsackievirus A7 reveals conformational changes associated with uncoating. J Virol. 2012 Jul;86(13):7207-15. doi: 10.1128/JVI.06425-11. Epub 2012 Apr 18. PMID: 22514349; PMCID: PMC3416324.
Coxsackie A9 IgG
Serum
belonging to the Picornavirus family