a-2 (female)

Plasma
check icon Optimal Result: 65 - 100 mg/dL.

The α-2 marker, one of the key HDL subpopulations measured by the Boston Heart HDL Map® test, plays an important role in assessing cardiovascular health. HDL, or high-density lipoprotein, is commonly known as "good cholesterol" because it helps remove bad cholesterol from the bloodstream. The α-2 HDL subclass is a specific type of HDL particle that carries cholesterol away from the arteries and back to the liver, where it can be processed and removed from the body. Measuring the levels of α-2 HDL can provide valuable insights into an individual's risk for cardiovascular disease (CVD). Higher levels of α-2 HDL are generally associated with better heart health because they indicate a more efficient removal of cholesterol, reducing the risk of plaque buildup in the arteries. Conversely, lower levels of α-2 HDL may suggest a higher risk of CVD because there is less HDL available to perform this vital function. By evaluating the amount of α-2 HDL in a patient's blood, healthcare providers can gain a more detailed understanding of their cardiovascular risk and tailor prevention or treatment strategies accordingly. This marker, along with others in the HDL Map test, helps paint a comprehensive picture of HDL function and cardiovascular health, moving beyond the basic measurement of total HDL cholesterol to more nuanced and actionable insights.

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What does it mean if your a-2 (female) result is too low?

Low levels of α-2 HDL signify an increased risk of cardiovascular disease (CVD) and are a concerning marker for heart health. α-2 HDL is a subclass of high-density lipoprotein that plays a vital role in removing cholesterol from the bloodstream and protecting the arteries from plaque buildup. When α-2 HDL levels are low, it indicates that the body's ability to clear cholesterol is compromised, potentially leading to the accumulation of cholesterol in the arteries and increasing the risk of heart attacks, strokes, and other cardiovascular events. Diagnosing low α-2 HDL levels typically involves a blood test, such as the Boston Heart HDL Map® test, which measures the various HDL subpopulations. Several factors can cause low α-2 HDL levels, including genetics, poor diet, lack of exercise, smoking, and certain medical conditions like diabetes and metabolic syndrome. Symptoms may not be directly noticeable, but the underlying risk manifests through signs of cardiovascular problems, such as chest pain, shortness of breath, and fatigue. Potential treatment options to address low α-2 HDL levels include lifestyle changes like adopting a heart-healthy diet low in saturated fats and cholesterol, increasing physical activity, quitting smoking, and maintaining a healthy weight. In some cases, medications that improve HDL function and overall cholesterol levels may be prescribed by a healthcare provider. These combined efforts aim to enhance α-2 HDL levels, thereby reducing the risk of future cardiovascular complications.

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I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with  any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.

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Frequently asked questions

Healthmatters is a personal health dashboard that helps you organize and understand your lab results. It collects and displays your medical test data from any lab in one secure, easy-to-use platform.

  • Individuals who want to track and understand their health over time.
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With a Healthmatters account, you can:

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Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:

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You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.

If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.

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