240 Food Panel: IgA, IgG, IgG4 (US BioTek)
Food sensitivities are recognized to be correlated with many chronic health conditions, such as IBS, eczema, fatigue, and others - but with proper identification and elimination of offending foods, many experience relief from their symptoms.
Food sensitivities are inflammatory responses of the immune system triggered by food allergens. Unlike food allergies, the symptoms of a food sensitivity often occur hours or even days after exposure, making it difficult to pinpoint the specific offending food(s). This delayed reaction is what causes the majority of the 12 million people estimated to suffer from food sensitivities unaware and blame things like aging for their chronic symptoms.
Testing for food sensitivities streamlines the process of identifying triggering foods, providing clear evidence and guidance to begin the healing process and start improving symptoms.
IgG is an antibody that can activate the pro-inflammatory complement system (complement cascade) associated with chronic inflammatory conditions. High levels of IgG (class II or higher) overload receptors and drive the inflammatory reaction while low levels of IgG (class 0/I) indicate tolerance.
IgG4 is an antibody which in most people does not activate the complement system, but instead is a blocking antibody for IgE. The presence of IgG4 is protective, not inflammatory, as IgG4/IgE binding tends to decrease IgE hypersensitivity (true allergy). If IgG4 is high, testing for IgE reactivity is advised and it may be best to remove the food from the diet permanently.
Independent increases in IgG4 only can be associated with certain autoimmune conditions such as eosinophilic esophagitis.
IgA is an antibody that can activate the pro-inflammatory complement system. Unlike Secretory IgA (sIgA) in stool, which is two IgA molecules bound together and secreted into the gut, serum IgA levels are associated with allergies and asthma. A Serum IgA reaction to food triggers can indicate foods that are irritating the lining of the gut.
Conditions and symptoms commonly associated with food sensitivity:
Brain Fog, Bloating, Weight Gain, Mood Swings, Joint Pain/Inflammation, Constipation, Diarrhea, Bronchitis, Crohn’s disease, Eczema, Migraines, GI distress, Stomach pain, Acne, ADD/ADHD, Autism, Sinus issues, Depression.
Biomarkers in this category
77 biomarkers · optimal ranges shown