Estrone (Pre-menopausal)

Optimal Result: 9.41 - 34.73 ng/mg Creat/Day.

Estrone is one of the three major naturally occurring estrogens, alongside estradiol and estriol.

Estrone, as a marker in a Human Urinary Metabolic Profile (HUMAP) panel for pre-menopausal women, offers valuable insights into estrogen metabolism and overall hormonal balance.

In pre-menopausal women, it plays a pivotal role in the menstrual cycle and overall reproductive health. Unlike estradiol, which is the predominant form of estrogen during the reproductive years, estrone becomes more significant after menopause. However, its levels and balance in pre-menopausal women are still crucial.

Elevated levels of estrone in this group can be indicative of various conditions such as estrogen dominance, which may manifest in symptoms like irregular menstrual cycles, weight gain, mood swings, and increased risk of uterine fibroids or endometriosis.

It can also be a marker for ovarian or adrenal tumors, which can produce estrogen independently. Conversely, low levels of estrone may suggest issues with ovarian function or hormonal imbalances that can impact fertility, bone health, and overall well-being.

Estrone levels are also influenced by body fat, as adipose tissue can convert androgens into estrogens, potentially leading to higher estrone levels in obese individuals. Additionally, factors such as stress, diet, and certain medications can affect estrone levels. Therefore, in a HUMAP panel, the measurement of estrone provides crucial data for understanding a woman's hormonal health, particularly in the context of symptoms suggestive of estrogen imbalance or in evaluating the risk of estrogen-related conditions.

Accurate interpretation of estrone levels requires a comprehensive approach, integrating this data with other clinical findings, patient history, and lifestyle factors to draw meaningful conclusions about a woman's hormonal status and health.

What does it mean if your Estrone (Pre-menopausal) result is too high?

Elevated levels of Estrone in pre-menopausal women, as indicated in a Human Urinary Metabolic Profile (HUMAP) panel, can signify a range of hormonal imbalances and health conditions, and addressing them involves a multifaceted approach:

→ Estrogen Dominance: High levels of Estrone may indicate estrogen dominance, a condition where the balance between estrogen and progesterone is skewed towards estrogen. This can lead to symptoms like irregular menstrual cycles, weight gain, mood swings, and an increased risk of hormone-related conditions like uterine fibroids or endometriosis.

→ Ovarian or Adrenal Tumors: In some cases, elevated Estrone levels can be a sign of ovarian or adrenal tumors that produce estrogen independently.

→ Obesity and Body Fat: Adipose tissue has the ability to convert androgens into estrogens, which can lead to higher Estrone levels in obese individuals.

To lower or treat elevated Estrone levels, several strategies can be employed:

→ Diet and Lifestyle Changes: Adopting a healthy diet rich in fiber and low in processed foods can help manage estrogen levels. Regular physical activity is also important, as it can help reduce body fat, which is directly linked to estrogen production.

→ Stress Management: Since stress can impact hormonal balance, incorporating stress-reduction techniques such as yoga, meditation, or regular exercise can be beneficial.

→ Hormonal Therapy: In some cases, hormonal therapies such as progesterone supplementation might be used to balance the estrogen/progesterone ratio.

→ Medications: If high Estrone levels are due to specific health conditions like tumors, appropriate medications or surgical interventions may be required.

→ Avoiding Environmental Estrogens: Reducing exposure to xenoestrogens, which are found in some plastics, personal care products, and pesticides, can help lower estrogen levels.

→ Liver Health: Supporting liver health through diet and supplements can aid in the efficient metabolism of estrogens.

→ Medical Supervision: Any approach to lowering Estrone levels should be done under medical supervision. A healthcare provider can offer guidance tailored to the individual's specific health needs, considering their overall health, symptoms, and medical history.

Overall, addressing elevated Estrone levels involves a comprehensive approach that includes lifestyle modifications, dietary changes, stress management, and possibly medical interventions, all tailored to the individual's unique health situation.

What does it mean if your Estrone (Pre-menopausal) result is too low?

Lower levels of Estrone in pre-menopausal women, as indicated in a Human Urinary Metabolic Profile (HUMAP) panel, can signify several health considerations, and increasing them typically involves a combination of lifestyle, dietary, and possibly medical interventions:

→ Ovarian Function Impairment: Low Estrone levels may suggest impaired ovarian function. This could be due to a variety of reasons, including premature ovarian failure or polycystic ovary syndrome (PCOS).

→ Hormonal Imbalances: Reduced levels of Estrone can be indicative of broader hormonal imbalances, possibly affecting fertility, menstrual regularity, and overall reproductive health.

→ Impact on Bone Health: Estrogen plays a crucial role in bone health. Low levels might increase the risk of conditions like osteoporosis, especially if the low estrogen state is prolonged.

→ General Health and Nutritional Status: Poor general health, including conditions like eating disorders or extreme physical stress (as seen in high-level athletes), can also lead to lower levels of Estrone.

To increase Estrone levels, various strategies can be considered:

→ Diet and Nutrition: Ensuring a balanced diet that includes sufficient fats and proteins is important, as these are essential for hormone production. Foods rich in phytoestrogens, like soy products, flaxseeds, and certain nuts, can mildly increase estrogen levels.

→ Managing Body Weight: Maintaining a healthy body weight is crucial. Both underweight and overweight conditions can disrupt estrogen production.

→ Stress Reduction: Chronic stress can impact hormone balance, so adopting stress management techniques like yoga, meditation, or regular exercise can be beneficial.

→ Hormone Replacement Therapy (HRT): In some cases, particularly where low Estrone is linked to menopausal changes or ovarian function impairment, hormone replacement therapy might be considered under the guidance of a healthcare provider.

→ Regular Exercise: While excessive exercise can lower estrogen levels, regular moderate exercise can help maintain a healthy hormonal balance and improve overall health.

→ Supplements: Some supplements, especially those that support general health and hormonal balance, might be recommended, but always under the supervision of a healthcare professional.

→ Regular Medical Checkups: Regular checkups can help monitor hormone levels and adjust any treatment plans as necessary.

It's important to approach the management of low Estrone levels holistically and under the guidance of healthcare professionals. They can provide personalized advice and treatment options based on the individual's overall health, symptoms, and specific medical needs.

Frequently asked questions

Unlock Your Health Journey with! Ever wished for a one-stop digital health haven for all your lab tests? Look no further! is your personalized health dashboard, bringing together test reports from any lab. Say goodbye to scattered results—organize and centralize your lab data effortlessly. Dive into the details of each biomarker and gain insights into the meaning behind your medical test data.

Join the community of thousands who've transformed the way they understand their lab results. Experience the joy of having all your lab data neatly organized, regardless of where or when the tests were done.

For our professional users, is a game-changer. Revel in the intuitive tools that not only streamline analysis but also save valuable time when delving into your client's lab report history. It's not just a dashboard; it's your gateway to a smarter, more informed health journey! personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:

  • The GI Effects® Comprehensive Stool Profile,
  • GI-MAP,
  • The NutrEval FMV®,
  • The ION Profile,
  • Amino Acids Profile,
  • Dried Urine Test for Comprehensive Hormones (DUTCH),
  • Organic Acids Test,
  • Organix Comprehensive Profile,
  • Toxic Metals,
  • Complete Blood Count (CBC),
  • Metabolic panel,
  • Thyroid panel,
  • Lipid Panel,
  • Urinalysis,
  • And many, many more.

You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.

If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.

While we do talk about popular labs, we welcome reports from lots of other places too. It's as simple as this: if you can get a test done, you can upload it to Healthmatters. We can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.

Still on the hunt for a specific biomarker? Just tell us, and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account!

There are two ways to add your test reports to your account. One option is to input the data using the data entry forms. The other method is to utilize our "Data entry service."

Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values.

For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you. We support various file types, including PDFs, JPGs, or Excel. This service is particularly useful if you have many reports to upload or if you're too busy to handle the data entry yourself.

Our special data entry service makes it easy to add your results to your private dashboard. Just attach an image or a file of your lab test results, and our skilled data entry team will do the work for you. It's all done by humans, ensuring that your data is entered accurately and with personal care for each client.

Depending on your account, the data entry service can be included for free or come at an additional cost of $15 per report.

For users on the Complete monthly plan, the first report is entered free of charge, and each additional report incurs a fee of $15.

Unlimited account holders enjoy the entry of ten reports without charge. Subsequent reports are subject to a $15 fee per report.

Additionally, users on the Complete plan can upgrade to a yearly subscription from the account settings. The annual subscription includes a data entry service for five reports.

The Unlimited plan is a one-time purchase for $250, and it covers your account for a lifetime with no additional payments.

For the Complete plan, the cost is $15 per month. You have the flexibility to cancel it anytime through your account settings, ensuring no further payments. To avoid charges, remember to cancel at least a day before the renewal date. Once canceled, the subscription remains active until the end of the current billing cycle.

Additionally, you can upgrade to the yearly Advanced plan from within your account. The annual cost is $79, and it comes with a data entry service for five reports.

You can always upgrade to a lifetime version with a prorated price from a monthly or yearly subscription.

Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.

Unlocking the insights from your lab tests has never been this intuitive! We've crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into a treasure trove of testing data.

1. Graph View:

Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.

2. All Tests View

Get a quick grasp of your test reports in minutes! Explore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.

3. Table View:

For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.

Experience the power of clear, organized data visualization with — your key to understanding and taking charge of your health journey!

Yes, you can download information from your account. We can compile your labs into a CSV file. To download all your labs, you can go to Account Settings, and at the bottom of the page, you will find a link to download your information.

Yes, you can print your report. To do so, navigate to "All tests" and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.

A personal account is all about keeping your own lab test results in check. It's just for you and your personal use.

The professional or business account is designed for health professionals who wish to track and organize their clients' laboratory results.

Use promo code to save 10% off any plan.

We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.