17-Hydroxyprogesterone (Post-menopausal)

Optimal Result: 0.12 - 0.65 ng/mg Creat/Day.

17-OH Progesterone is the product of progesterone hydroxylation.

What does it mean if your 17-Hydroxyprogesterone (Post-menopausal) result is too low?

There is very little research pertaining to low levels of this metabolite, making its clinical significance unknown. Low levels of the precursor hormones pregnenolone, 17-hydroxypregnenolone, and progesterone can contribute to decreased levels.

What does it mean if your 17-Hydroxyprogesterone (Post-menopausal) result is too high?

17-OH Progesterone is the product of progesterone hydroxylation. Elevations are associated with PCOS, idiopathic hirsutism, congenital adrenal hyperplasia, 11-beta-hydroxylase deficiency, and adult onset viralizing adrenal hyperplasia. Additionally, hyperinsulinemia and hyperglycemia (metabolic syndrome) push 17-hydroxylation of progesterone.

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