Pancreatic Elastase 1


A healthy result should fall into the range 200 - 1000 mcg/g.

The pancreatic elastase 1 fecal test is used to diagnose insufficiencies of the pancreas that result in diseases such as:

- Cystic fibrosis

- Chronic pancreatitis

- Pancreatic cancer

- Inflammatory Bowel Disease

- Gallstones

- Diabetes, Type 1

- Shwachman-Diamond Syndrome

In many of these conditions, there is often diarrhea, weight loss, undigested food in the stool, and pain in the abdomen. If the condition continues for a longer period of time, then low bone density may be found.

This test is an excellent biomarker for how well the pancreas is working because the enzyme pancreatic elastase I is not broken down by what happens in the intestinal tract. The Elastase I protein is found concentrated in the stool, five times higher than what is found in pancreatic juice. 

Normal Ranges for Pancreatic Elastase in ug/gram fecal matter:

Normal: >200 ug elastase/gram fecal matter

Severe pancreatic insufficiency: <100 ug elastase/gram fecal matter

Moderate pancreatic insufficiency: 100-200 ug elastase/gram fecal matter




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