The predominant genera in the human colonic microbiota are Bacteroides and Prevotella, which belong to the major phyla Bacteroidetes. Their composition and metabolic activities are largely modulated by diet and, in addition, they can also affect the metabolism of food. Prevotella is associated with plant-rich diets (high levels of complex carbohydrates and fruit and vegetable intake), whereas Bacteroides is linked to a high intake of fat and protein. Bacteroides and Prevotella species have their own specific habitats in the human body as they are antagonistic.
-----------------------
- Bacteroides historically included multiple taxonomic groups including Prevotella and others. New classification has separated them into
Bacteroides,Prevotella, and other groups, however it is challenging to separate many of the species. For this reason, the Bacteroides /Prevotella group includes mainly Bacteroides and some Prevotella.
- Displays flexibility to adapt to many environmental conditions/diets Bacteroidesconsist of bile-tolerant organismsand has the capability of
utilizing polysaccharidesand mucins.
- Produces beta glucuronidase, secondary bile acids, acetate, propionate, products of protein breakdown, and is involved in
vitamin metabolism.
- Associated with reduced bacterial gene richness
- Along with Methanobrevibacter smithii, certain Clostridium and Bacteroides spp. can produce methane gas.
- Generally associated with industrialized populations consuming a Western diet.
- Bacteroides growth in culture and propionate formation is favored at a close-to-neutral pH of 6.5, in contrast to butyrate-producing
Faecalibacterium prausnitziiand Roseburia spp., which arefavored at a lower pH of 5.5.
References:
- https://www.cell.com/cell-metabolism/abstract/S1550-4131(15)00517-3
- https://www.nature.com/articles/nrgastro.2016.4
- https://www.gdx.net/core/supplemental-education-materials/Commensal-Bacteria-Chart.pdf
- Tart cherry juicemay normalize high or low levels.
- Reduced with inulin from Jerusalem artichoke or chicory. A systematic review of inulin supplementation in humans showed an increase in Bifidobacterium, and a relative increase in Faecalibacterium and Lactobacillus, and decrease in relative abundance of Bacteroides.
- Lactobacillus kefiri was given to 20 healthy volunteers for one month and after the probiotic was discontinued for a month, Bacteroides, Barnesiella, Clostridium, Veillonellaand other species were significantly reduced compared to baseline samples.
- A study on 250 vegetarian and vegan individuals showed lower counts of Bifidobacterium spp. (vegan), Bacteroides spp. (vegan) and E. coli (vegan and vegetarian).
Understand and improve your laboratory results with our health dashboard.
Upload your lab reports and get interpretation today.
Our technology helps to understand, combine, track, organize, and act on your medical lab test results.
Increased Levels
- A Bacteroides-dominated microbiomeispositively correlated with long-term diets rich in animal protein and saturated fat. A small study on 11 healthy volunteers showed that an animal-baseddiet increased the abundance of bile-tolerant microorganisms (Alistipes, Bilophilaand Bacteroides) and decreased the levels of Firmicutes that metabolize dietary plant polysaccharides (Roseburia, Eubacterium
rectaleand Ruminococcus bromii).
- Tart cherry juicemay normalize high or low levels.
- Increased in obese adolescents who lost more than 4 kg on a calorie-restricted diet
- Increased in overweight men drinking low glycinin soymilk compared to regular soymilk or bovine milk
- Levels of Bacteroides, Faecalibacterium, Odoribacter, and others enrichedafter pomegranate extract consumption in overweight-obese subjects. Serum endotoxemia marker LBP was reduced.
Four bacteria are enriched with aspirin use versus no medication and includes Bacteroides spp., Prevotella spp., Barnesiella spp. and the family Ruminococaceae. Furthermore, Bacteroidesspp. was seen with other medications including NSAIDs with PPIs, and NSAIDs with antidepressants and laxatives.
- Cigarette smoking is associated with increased levels.
- Red wine was positively associated with the relative abundance of Bacteroides in 23
allergic patients, 25 and in 10 healthy males.
- A high beef diet was associated with increases in Bacteroidesfragilis, B. vulgatusand Clostridium spp. in 10 volunteers.
- A ketogenic low-carbohydrate high-fat diet was associated with a reduction of Faecalibacterium and abundance of Bacteroides and Dorea spp. in race walkers.
Interpret Your Lab Results
Upload your lab report and we’ll interpret and provide you with recomendations today.
Get Started
Get Started With Our Personal Plan
Advanced Plan
Unlimited Plan
Are You a Health Professional?
Get started with our professional plan
Welcome to Healthmatters Pro.
Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place. Learn more
Pro Plan
for health professionals
$45 per month
At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.
Acetate, Akkermansia muciniphila, Anaerotruncus colihominis, Anaerotruncus colihominis/massiliensis, Ancylostoma/Necator (Hookworm), Ascaris lumbricoides, Bacteroides uniformis, Bacteroides vulgatus, Bacteroides-Prevotella group, Barnesiella spp., Beta-glucuronidase, Bifidobacterium longum, Bifidobacterium longum subsp. longum, Bifidobacterium spp., Blastocystis spp., Butyrivibrio crossotus, Calprotectin, Candida albicans/dubliniensis, Capillaria philippinensis, Cholesterol, Citrobacter species, Clostridium spp., Collinsella aerofaciens, Coprococcus eutactus, Cryptosporidium parvum/hominis, Cyclospora cayetanensis, Desulfovibrio piger, Dientamoeba fragilis, Entamoeba histolytica, Enterobacter cloacae, Enterobius vermicularis, Enterococcus faecalis, Eosinophil Protein X, Escherichia coli, Faecalibacterium prausnitzii, Fecal Color, Fecal Consistency, Fecal Fat, Total, Fecal Occult Blood, Fecal secretory IgA, Firmicutes/Bacteroidetes (F/B Ratio), Fusobacterium spp., Giardia, Klebsiella oxytoca, Klebsiella species, Lactobacillus spp., Long-Chain Fatty Acids, Methanobrevibacter smithii, n-Butyrate %, n-Butyrate Concentration, Odoribacter spp., Oxalobacter formigenes, Pancreatic Elastase 1, Phocaeicola vulgatus, Phospholipids, Prevotella spp., Products of Protein Breakdown (Total), Propionate, Proteus mirabilis, Pseudoflavonifractor spp., Roseburia spp., Ruminococcus bromii, Ruminococcus spp., Short-Chain Fatty Acids (SCFA), Total, Triglycerides, Veillonella spp., Zonulin Family Peptide
