Optimal Result: 14000000 - 1900000000 CFU/g stool.

Collinsella aerofaciens is a group of bacteria found in the gut and also on the surface of the tongue. It is named after the microbiologist Matthew Collins.

The species name aerofaciens comes from the Greek words “aeros” (gas) and “faciens”, (producing).

The species of the Collinsella genus are known for their ability to ferment a wide range of carbohydrates, including starch, forming products such as hydrogen gas and ethanol.

A reduced abundance of this group of bacteria has been related with more severe symptoms in patients suffering from irritable bowel syndrome.

References: 

- Kassinen, A., Krogius-kurikka, L., Paulin, L., Corander, J., Malinen, E., Apajalahti, J., & Palva, A. (2007). The Fecal Microbiota of Irritable Bowel Syndrome Patients Differs. Gastroenterology, 133, 24–33. 

- Walker, A. W., Ince, J., Duncan, S. H., Webster, L. M., Holtrop, G., Ze, X., Flint, H. J. (2011). Dominant and diet-responsive groups of bacteria within the human colonic microbiota. The ISME Journal, 5(2), 220–230.

- Tyrrell, K. L., Citron, D. M., Warren, Y. A., Nachnani, S., & Goldstein, E. J. C. (2003). Anaerobic bacteria cultured from the tongue dorsum of subjects with oral malodor. Anaerobe, 9, 243–246.

- Gomez-Arango, Luisa F et al. “Low dietary fiber intake increases Collinsella abundance in the gut microbiota of overweight and obese pregnant women.” Gut microbes vol. 9,3 (2018): 189-201. doi:10.1080/19490976.2017.1406584

What does it mean if your Collinsella aerofaciens result is too low?

Decreased on a high-protein, low-carb weight loss diet in a study in 14 overweight men. 

C. aerofaciens reduced in elderly subjects taking NSAIDs compared to elderly subjects not taking NSAIDs, or in young adults.

Oral versus IV iron supplementation in iron-deficient IBD patients resulted in decreased abundances of Faecalibacterium prausnitzii, Ruminococcus bromii, Dorea spp., and Collinsella aerofaciens.

What does it mean if your Collinsella aerofaciens result is too high?

Higher C. aerofaciens levels in healthy adults consuming a whole grain diet (40 g fiber) compared to red meat diet. 

Studies are mixed on the association with fiber and the Collinsella genus, which contains at least 6 species.

Higher levels were found in non-vegetarian versus vegetarian Thai adults that were healthy.

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