GI Effects Stool Profile | Genova Diagnostics

Bifidobacterium longum subsp. longum

Optimal Result: 0 - 130000000 CFU/g stool.

Bifidobacterium longum is comprised of multiple subspecies that beneficially modulate the immune system. It is found in probiotic supplements and fermented foods. Lactate producer; acetate producer. 

Utilizes diet-derived carbohydrates. 

References:

O’Callaghan A, van Sinderen D. Bifidobacteria and Their Role as Members of the Human Gut Microbiota. Front Microbiol. 2016;7:925.

Wong CB, Odamaki T, Xiao J-z. Beneficial effects of Bifidobacterium longum subsp. longum BB536 on human health: Modulation of gut microbiome as the principal action. J Function Foods. 2019;54:506-519.

Haro C, Garcia-Carpintero S, Alcala-Diaz JF, et al. The gut microbial community in metabolic syndrome patients is modified by diet. J Nutr Biochem. 2016;27:27-31.

Li J, Hou Q, Zhang J, et al. Carbohydrate Staple Food Modulates Gut Microbiota of Mongolians in China. Front Microbiol. 2017;8:484.

Cox SR, Lindsay JO, Fromentin S, et al. Effects of Low FODMAP Diet on Symptoms, Fecal Microbiome, and Markers of Inflammation in Patients With Quiescent Inflammatory Bowel Disease in a Randomized Trial. Gastroenterology. 2020;158(1):176-188. e177.

De Palma G, Nadal I, Collado MC, Sanz Y. Effects of a gluten-free diet on gut microbiota and immune function in healthy adult human subjects. Br J Nutr. 2009;102(8):1154-1160.

What does it mean if your Bifidobacterium longum subsp. longum result is too low?

B. longum and B. adolescentis suppressed by rice in 26 Mongolian individuals who consumed wheat, rice, and oat as the sole carbohydrate staple food for a week each.

A low FODMAP diet in 52 IBD patients resulted in lower Bifidobacterium adolescentis, Bifidobacterium longum, and Faecalibacterium prausnitzii than patients on a control diet. However, microbiome diversity and markers of inflammation did not differ between the IBD and control groups.

A small study of 10 healthy subjects showed reduced Lactobacillus, Bifidobacterium and Bifidobacterium longum after 1 month on a gluten-free diet (GFD).

What does it mean if your Bifidobacterium longum subsp. longum result is too high?

Long-term consumption of Mediterranean diet partially restored B. longum in metabolic syndrome patients.

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