Faecalibacterium prausnitzii

Faecalibacterium prausnitzii is one of the most important bacteria in the human gut flora and makes up to 5-10% of the total number of bacteria detected in stool samples from healthy humans. Faecalibacterium prausnitzii has a crucial role in maintaining gut physiology and host wellbeing.

Faecalibacterium prausnitzii monitoring may serve as a biomarker to assist in gut diseases diagnostics.

Faecalibacterium prausnitzii has been consistently reported as one of the main butyrate producers found in the intestine. Butyrate has a crucial role in gut physiology and host wellbeing. It is the main energy source for the colonocytes and it has protective properties against colorectal cancer (CRC) and inflammatory bowel diseases.

• Faecalibacterium prausnitzii serves as energy sources for the colonocytes and have anti-inflammatory effects and maintain the activity of bacterial enzymes and protects the digestive system against intestinal pathogens.
• Faecalibacterium prausnitzii has various anti-inflammatory properties [L]
• Faecalibacterium prausnitzii has also been shown to reduce the severity of inflammation [L]
• There seems to be a possible protective benefit of F. prausnitzii against the development of IBD. [L]

References:

• Faecalibacterium prausnitzii: from microbiology to diagnostics and prognostics [L]
• Action and function of Faecalibacterium prausnitzii in health and disease [L]
• Association between Faecalibacterium prausnitzii Reduction and Inflammatory Bowel Disease: A Meta-Analysis and Systematic Review of the Literature [L]
• Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients [L]