Fecal secretory IgA

Stool

A healthy result should fall into the range 0 - 885 mcg/g.

Fecal Secretory IgA is a marker of gut secretory immunity and barrier function.

Immunoglobulin A (IgA) is an antibody playing a critical role in mucosal immunity and is produced in greater quantities than all other types of antibody combined.

In its secretory form, Secretory IgA is the main immunoglobulin found in mucous secretions and provides protection against potentially pathogenic microbes, due to its ability to resist degradation by enzymes and survive in harsh environments such as GI and respiratory tracts.

Secretory IgA is the first line of defense against:

  • bacteria
  • food residues
  • yeast
  • parasites

Lifestyle and nutritional factors influence levels. Choline, EFA’s, glutathione, glycine, phosphatidylcholine, Vitamin C & zinc are all needed for efficient production.

References:

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845795/

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